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oai:figshare.com:article/34515007 2026-10-14T17:47:19Z category_7 category_8 category_12 category_14 category_15 category_272 category_106 category_46 category_734 category_811 category_64 category_132 category_134 category_135 portal_5 item_type_3 month_year_10_2026

<p>Extended regulon connectivity table listing transcription factors and their inferred target genes.</p> Seth Frietze (235719) Cameron Lunn (25823770) Dean Oldham (11740823) Joseph R. Boyd (6877823) Andrew N. Bubak (6273827) Amalia Bustillos Saucedo (25823773) Maria A. Nagel (6459632) Diego Restrepo (326481) Kimberley D. Bruce (13041708) Christy S. Niemeyer (10494361) Medicine Microbiology Cell Biology Molecular Biology Neuroscience Environmental Sciences not elsewhere classified Science Policy Immunology Biological Sciences not elsewhere classified Mathematical Sciences not elsewhere classified Cancer Infectious Diseases Virology Computational Biology term neurological vulnerability sustained neuroinflammatory activity shape microglial responses remain poorly understood neurotropic pathogen capable initial immune response g ., apoe epigenetically distinct microglial driven regulatory programs chromatin accessibility profiling central nervous system cell regulatory architecture cell multiome analysis discrete brainstem regions inferred transcriptional networks div >< p complementary spatial proteomics reduced following hsv associated populations characterized hsv ‑ 1 spatial proteomics positive regions vivo </ vivo ,</ neurodegenerative disease molecular mechanisms microglia orchestrate microglia dominated marked overrepresentation macrophage populations lineage states homeostatic signatures first time epigenetic remodeling epigenetic mechanisms cst3 </ cognitive impairment chronic neuroinflammation cebpb </ 1 infection 1 antigen <p>Extended regulon connectivity table listing transcription factors and their inferred target genes.</p> 2026-10-14T17:47:04Z Dataset Dataset 10.1371/journal.ppat.1014684.s009 https://figshare.com/articles/dataset/_p_Extended_regulon_connectivity_table_listing_transcription_factors_and_their_inferred_target_genes_p_/34515007 CC BY 4.0