2026-10-15T15:28:31Z https://api.figshare.com/v2/oai

oai:figshare.com:article/34487523 2026-10-14T14:13:42Z category_24382 category_24388 category_24361 portal_753 item_type_3 month_year_10_2026

Phytophthora cinnamomi RxLR effectors induce cell death and activate immune responses in Nicotiana benthamiana Ncobile Kunene (25781592) Velushka Swart (17847012) Lucy Moleleki (3432491) Noelani van den Berg (20312979) Plant cell and molecular biology Plant pathology Microbial genetics Cell death Phytophthora cinnamomi RxLR effector Localisation Plant defence Nicotiana benthamiana Planta Immune response SDG 2 Zero hunger SDG 3 Good health and wellbeing SDG 12 Responsible consumption and production SDG 15 Life on land <p dir="ltr">Phytophthora cinnamomi is a destructive oomycete pathogen that secretes effector proteins, including RxLRs, to manipulate host immunity during infection. Although several P. cinnamomi RxLR effectors have previously been identified, their functional roles remain poorly understood. In this study, 16 candidate RxLR effectors were transiently expressed in Nicotiana benthamiana to investigate their localisation and biological activity. The effectors displayed diverse subcellular localisation patterns, including the nucleus, cytoplasm, and plasma membrane. Five candidates induced cell death in planta. PcinRxLR72 required nuclear localisation for its cell death-inducing activity. Expression of PcinRxLR72 also promoted reactive oxygen species accumulation and activated plant immune responses. These findings provide insight into the functional roles of P. cinnamomi RxLRs and an important foundation for future studies of P. cinnamomi – plant interactions.</p> 2026-10-14T14:13:42Z Dataset Dataset 10.25403/UPresearchdata.34487523.v1 https://figshare.com/articles/dataset/Phytophthora_cinnamomi_RxLR_effectors_induce_cell_death_and_activate_immune_responses_in_Nicotiana_benthamiana/34487523 CC BY 4.0