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oai:figshare.com:article/34074038 2026-10-05T17:56:43Z category_1 category_7 category_12 category_13 category_21 category_734 category_931 category_64 category_133 portal_5 item_type_2 month_year_10_2026

<p>Cryo-ET movie of wild-type <i>S. cerevisiae</i> showing cytosol with ribosomes and peripheral ER subdomains, including plasma membrane–associated ER (pmaER) and tubular ER (tubER).</p> Tianyu Wu (2009116) Marie-Christin Spindler (25317353) Abner T. Apsley (14146362) Emmy Earnest (25317356) Zane R. Thornburg (11169477) Julia Mahamid (10496445) Zaida Luthey-Schulten (227919) Biophysics Medicine Cell Biology Genetics Biotechnology Biological Sciences not elsewhere classified Information Systems not elsewhere classified Cancer Plant Biology ribosomes physically bound physical proximity ), ordinary differential equations modulate regulatory dynamics local reaction rules budding yeast (< derived intracellular architectures saccharomyces cerevisiae </ gal2p abundance occurs including chromosome organization intracellular spatial heterogeneity established galactose switch div >< p intracellular organization galactose switch spatial positions gal2p output gal2 </ subcellular organization transport processes spatially organized results demonstrate resolved models react regardless quantitative gene plasma membrane motivating integration modeled using mixed environment little effect largest decrease integrate experimentally gene expression future whole eukaryotic cells enforces locality endoplasmic reticulum electron microscopy distinct compartments develop spatially biochemical constraints <p>Cryo-ET movie of wild-type <i>S. cerevisiae</i> showing cytosol with ribosomes and peripheral ER subdomains, including plasma membrane–associated ER (pmaER) and tubular ER (tubER).</p> 2026-10-05T17:56:32Z Dataset Media 10.1371/journal.pcbi.1014811.s007 https://figshare.com/articles/media/_p_Cryo-ET_movie_of_wild-type_i_S_cerevisiae_i_showing_cytosol_with_ribosomes_and_peripheral_ER_subdomains_including_plasma_membrane_associated_ER_pmaER_and_tubular_ER_tubER_p_/34074038 CC BY 4.0