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oai:figshare.com:article/34073746 2026-10-05T17:52:37Z category_7 category_13 category_14 category_21 category_106 category_132 category_134 portal_5 item_type_3 month_year_10_2026

<p>Internationally adapted rabies pre-exposure prophylaxis (PrEP) risk categories and recommendations. Risk categories and recommendations for PrEP, rabies virus-neutralising antibody (RVNA) titre monitoring, and booster vaccination are adapted from the 2022 United States Advisory Committee on Immunization Practices (ACIP) rabies PrEP recommendations and the 2025 CDC guidance [58]. Occupational and exposure descriptions have been simplified for international application while preserving the original risk stratification.</p> Stuart D. Blacksell (9740220) Khanh Kim Le (17981612) Paola De Benedictis (405039) Morgane Gourlaouen (8430900) Medicine Genetics Molecular Biology Biotechnology Science Policy Infectious Diseases Virology potentially infectious materials personal protective equipment high fatality rate existing preventive measures clinical symptoms develop almost always fatal sample handling procedures strict biosafety measures current biosafety practices based biosafety protocols key diagnostic procedures validating inactivation methods biosafety risks associated handling rabies virus virus inactivation rabies virus biosafety constraints laboratory handling physical methods decontamination methods rabies diagnostic acquired rabies viral encephalomyelitis transmission pathways strengthening evidence research laboratories require validation related lyssaviruses particular attention limited settings knowledge gaps documented cases diagnostic standardisation comprehensive review <p>Internationally adapted rabies pre-exposure prophylaxis (PrEP) risk categories and recommendations. Risk categories and recommendations for PrEP, rabies virus-neutralising antibody (RVNA) titre monitoring, and booster vaccination are adapted from the 2022 United States Advisory Committee on Immunization Practices (ACIP) rabies PrEP recommendations and the 2025 CDC guidance [<a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0014757#pntd.0014757.ref058" target="_blank">58</a>]. Occupational and exposure descriptions have been simplified for international application while preserving the original risk stratification.</p> 2026-10-05T17:52:32Z Dataset Dataset 10.1371/journal.pntd.0014757.t004 https://figshare.com/articles/dataset/_p_Internationally_adapted_rabies_pre-exposure_prophylaxis_PrEP_risk_categories_and_recommendations_Risk_categories_and_recommendations_for_PrEP_rabies_virus-neutralising_antibody_RVNA_titre_monitoring_and_booster_vaccination_are_adapted_fr/34073746 CC BY 4.0