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oai:figshare.com:article/34073242 2026-10-05T17:45:12Z category_1 category_915 category_7 category_8 category_12 category_13 category_15 category_19 category_734 category_64 portal_5 item_type_3 month_year_10_2026

<p>Source data for Fig 4 and 6.</p> Eyson Quiceno (25317202) Cristian Camilo Rodríguez-Almonacid (25317205) Khalid Omeir (23864316) Jacob Ancira (23864304) Caleb Phillips (469277) Zemfira N. Karamysheva (25317208) Biophysics Physical Sciences not elsewhere classified Medicine Microbiology Cell Biology Genetics Neuroscience Pharmacology Biological Sciences not elsewhere classified Cancer therapeutic interventions aimed several biological processes rechallenge phases revealed potassium antimonyl tartrate initiating ribosome biogenesis heavy metal transporters div >< p coordinated survival reprogramming biological processes associated survive immediate toxicity profile rapidly reverted induce dormant state upon drug removal transient state constitutes supporting epitranscriptomic changes induced drug tolerance increased drug tolerance viable promastigote persister leishmania mexicana </ disorganized drug response parental parasites displayed epitranscriptomic changes tolerance genes transient ability survive exposure rapidly implementing growing state adapted state leishmania </ epitranscriptomic modulators drug response uniquely downregulated treatment failure tested conditions resume proliferation protein synthesis parental parasites nucleolar pathways mitochondrial functions mitochondrial function major driver maintain viability killed 80 highly conserved global remodeling free recovery free medium <p>Differential gene expression of comparisons 1–6 (C1-6).</p> <p>(XLSX)</p> 2026-10-05T17:45:03Z Dataset Dataset 10.1371/journal.ppat.1014682.s006 https://figshare.com/articles/dataset/_p_Source_data_for_Fig_4_and_6_p_/34073242 CC BY 4.0