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oai:figshare.com:article/34073215 2026-10-05T17:45:00Z category_1 category_4 category_8 category_12 category_13 category_734 category_61 category_64 category_132 category_134 portal_5 item_type_3 month_year_10_2026

<p>The PrsA2 C-tail is required for secreted LLO activity at pH 5.0 and pH 6.5.</p> Allison H. Kumar (25317196) Charles Agbavor (22120874) Francis Alonzo 3rd (25317199) Laty A. Cahoon (8500875) Biophysics Biochemistry Microbiology Cell Biology Genetics Biological Sciences not elsewhere classified Developmental Biology Cancer Infectious Diseases Virology wall targeting antibiotics wall active antibiotics uncharacterized unstructured region peptidyl prolyl isomerase mouse septicemic model div >< p adopting multiple conformations condition specific protein secreted proteins including pore forming toxin listeria monocytogenes </ secreted protein function secretion chaperone prsa2 tail bacterial mutants protein interactions llo toxin chaperone proteins chaperone function lm </ bacterial virulence work characterizes virulence defect use biophysical stress conditions prsa2 contains prsa homologs promotes pathogenesis positive bacteria often sites llo ). functional activity foldase domain flexible regions crucial role biochemical assays >), prsa2 <p>The PrsA2 C-tail is required for secreted LLO activity at pH 5.0 and pH 6.5.</p> 2026-10-05T17:44:17Z Dataset Dataset 10.1371/journal.ppat.1014676.t001 https://figshare.com/articles/dataset/_p_The_PrsA2_C-tail_is_required_for_secreted_LLO_activity_at_pH_5_0_and_pH_6_5_p_/34073215 CC BY 4.0