2026-10-06T14:37:52Z
https://api.figshare.com/v2/oai
oai:figshare.com:article/34073009
2026-10-05T17:43:06Z
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<p>Delamanid (DLM) and pretomanid (Pa) minimum inhibitory concentrations (MICs), genomic variants, lineage, and clinical characteristics of 17 <i>Mycobacterium tuberculosis</i> isolates included in the study.</p>
Ana Tsutsunava (22624112)
Nestani Tukvadze (333421)
Zaza Avaliani (7517621)
Galo A. Goig (8286999)
Levan Jugheli (476405)
Sebastien Gagneux (149824)
Russell R. Kempker (7348955)
Nino Maghradze (7517618)
Microbiology
Genetics
Molecular Biology
Pharmacology
Biotechnology
Evolutionary Biology
Environmental Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
Immunology
Biological Sciences not elsewhere classified
Cancer
Hematology
Infectious Diseases
Virology
whole genome sequencing
resazurin microtiter assay
rapid molecular diagnostics
div >< p
47 %) manifested
2021 – 2024
minimum inhibitory concentrations
remaining nine isolates
hinder resistance detection
isolates phenotypically resistant
mycobacterium tuberculosis </
results support dlm
routine pdst using
identify mutations associated
pa resistance association
dlm concentration range
pa resistance (<
resistant tuberculosis
critical concentrations
determined using
broader range
three isolates
w678g mutations
conferring mutations
emerging resistance
drug resistance
mtb </
fgd1 </
fbic </
ddn </
pa resistance
wgs ).
treatment outcomes
threatens drug
standardization challenges
respectively ).
one carrying
mic value
<p>Delamanid (DLM) and pretomanid (Pa) minimum inhibitory concentrations (MICs), genomic variants, lineage, and clinical characteristics of 17 <i>Mycobacterium tuberculosis</i> isolates included in the study.</p>
2026-10-05T17:43:00Z
Dataset
Dataset
10.1371/journal.pone.0359717.t001
https://figshare.com/articles/dataset/_p_Delamanid_DLM_and_pretomanid_Pa_minimum_inhibitory_concentrations_MICs_genomic_variants_lineage_and_clinical_characteristics_of_17_i_Mycobacterium_tuberculosis_i_isolates_included_in_the_study_p_/34073009
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