2026-10-06T08:17:53Z https://api.figshare.com/v2/oai

oai:figshare.com:article/34056318 2026-10-02T11:23:02Z category_1 category_4 category_146 category_12 category_19 category_21 category_272 category_873 category_39 category_45 category_734 category_61 portal_63 item_type_3 month_year_10_2026

A Base Promoted Synthesis of Indazolo[2,3‑a]quinolines from Isatogens and 2‑(2-Aminophenyl)acetonitriles Hunmoina Phukon (23106766) Moasosang Aier (25301973) Anil K. Saikia (1608139) Biophysics Biochemistry Space Science Cell Biology Pharmacology Biotechnology Environmental Sciences not elsewhere classified Chemical Sciences not elsewhere classified Ecology Sociology Biological Sciences not elsewhere classified Developmental Biology c – n c – c 3 ‑< italic 2 ‑( 2 2 -( 2 base promoted synthesis promoted one 3 -< synthetic utility simultaneous formation A transition-metal-free, base-promoted one-pot cascade cyclization strategy has been developed for the construction of indazolo[2,3-<i>a</i>]quinolines utilizing isatogens and 2-(2-aminophenyl)acetonitriles as precursors. This protocol enables the simultaneous formation of C–C, C–N, and N–N bonds to access complex tetracyclic frameworks. Preliminary photophysical characterization reveals significant fluorescence emission, indicating that the compound possesses promising optical properties for further investigations. The synthetic utility of this protocol is further underscored by its application in the Rh-catalyzed construction of highly-fused polycyclic cinnolinium salts. 2026-10-02T00:00:00Z Dataset Dataset 10.1021/acs.joc.6c01674.s001 https://figshare.com/articles/dataset/A_Base_Promoted_Synthesis_of_Indazolo_2_3_a_quinolines_from_Isatogens_and_2_2-Aminophenyl_acetonitriles/34056318 CC BY-NC 4.0