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oai:figshare.com:article/34054620 2026-10-02T05:37:42Z category_15 portal_316 item_type_3 month_year_10_2026

Data Sheet 1_Digital mobility assessment using wearable devices in people with Parkinson’s disease: a feasibility and implementation study in Ghana (TraPCAf) compared with a UK cohort.docx Metin Bicer (25162701) Cameron Kirk (9750274) Mary Agoriwo (25162704) Momodou Cham (3498860) Albert Akpalu (5982842) Njideka Okubadejo (376251) Javad Sarvestan (9954874) Jack Lumsdon (19816468) Yasin Okkaoglu (20392831) Katie Brittain (6528689) Ríona McArdle (17053512) Lisa Alcock (5965478) Alison J. Yarnall (9522476) Natasha Fothergill-Misbah (23635104) Richard Walker (3126456) Lynn Rochester (286468) Silvia Del Din (11307439) TraPCAf (25162707) Neuroscience Africa digital health technology digital mobility outcomes gait real-world feasibility Parkinson’s disease wearable sensor Introduction<p>Life expectancy is rising in Africa, increasing Parkinson’s disease (PD) prevalence. PD in Africa is often underdiagnosed/undertreated due to limited specialists, awareness and medication access. Gait impairments are among the earliest and most disabling PD symptoms, yet their presentation in African populations is poorly understood. This study aimed to (1) compare real-world mobility between PD and older controls in a population from Ghana (GHA-PD and GHA-CL), (2) examine associations between digital mobility outcomes (DMOs) and clinical/demographic factors between GHA-PD and a PD cohort from a high-income European country (UK-PD), and (3) assess the acceptability of the measurement method in GHA-PD and GHA-CL.</p>Methods<p>PD (n = 50) and controls (n = 30) in Ghana wore a wearable device (Axivity AX6) for seven days. Raw data were used to derive 24 DMOs using the Mobilise-D pipeline. An age-gender-matched PD and control cohort (UK-CL), based in United Kingdom, from another study was included for comparison. Differences were also analysed by controlling confounding factors.</p>Results<p>Sixteen of 24 DMOs differed significantly (p < 0.05) between GHA-PD and GHA-CL (steps per day: 2153 vs. 10001, daily walking time: 0.43 vs. 2.07 hours). Mobility impairment was more pronounced in GHA-PD than UK-PD, with differences remaining in 18 DMOs after adjustment for confounding factors. Feasibility and acceptability were high, although discomfort was commonly reported.</p>Discussion<p>Reduced mobility and gait quality in GHA-PD highlight risks of functional decline and loss of independence. Further research should investigate lifestyle, cultural, environmental and healthcare factors that might contribute to these disparities.</p> 2026-10-02T05:37:42Z Dataset Dataset 10.3389/fnagi.2026.1899045.s001 https://figshare.com/articles/dataset/Data_Sheet_1_Digital_mobility_assessment_using_wearable_devices_in_people_with_Parkinson_s_disease_a_feasibility_and_implementation_study_in_Ghana_TraPCAf_compared_with_a_UK_cohort_docx/34054620 CC BY 4.0