2026-10-13T08:50:22Z https://api.figshare.com/v2/oai

oai:figshare.com:article/34049638 2026-10-01T17:51:39Z category_7 category_15 category_21 category_734 category_61 category_122 category_132 portal_5 item_type_1 month_year_10_2026

<p>Long-range synapses experience delayed spike synchrony.</p> Felix Benjamin Kern (17145132) Takahisa Date (25158079) Zenas C. Chao (17145135) Medicine Neuroscience Biotechnology Biological Sciences not elsewhere classified Developmental Biology Mental Health Infectious Diseases supercritical behavior compared spike pairs outside related systems organized optimal information processing network &# 8217 stochastic intrinsic activity resulting network activity spiking neural networks operate near criticality dimensional spiking networks allow synaptic weights inhibitory connectivity influences range inhibitory synapses development towards criticality range synapses synaptic weights inhibitory connectivity synaptic delays inhibitory plasticity full connectivity weaker long systematically constrain storage capabilities spatially distributed spatial organization spatial constraints similar number signal timing potentiation window low level key determinant dynamical development development due critical point <p><b>(A)</b> Spike coincidence plots for inhibitory synapses in a sample network ( mm, ), sorted by connection length from the shortest connections (left) to the longest connections (right). The top panel shows the average weight of the connections over development, while the bottom panel shows the density of spikes paired within ±50 ms at their respective . The white horizontal lines indicate the boundaries of the potentiation window of the inhibitory STDP rule. Spike timing is measured locally at the synapse, mirroring the STDP weight update procedure. <b>(B)</b> The same data summed over development time and plotted as lines. The shaded area indicates the potentiation window of the inhibitory STDP rule. <b>(C)</b> The same data but using the global timing of spikes instead of the timing local to each synapse. <b>(D, E)</b> Relating synaptic distance, grouped into bins of width 0.4 mm, to spike coincidence across all networks in the final hour of simulation. <b>D</b>: Mean absolute spike-timing difference (|Δt|) in each bin. <b>E</b>: Fraction of spike pairs within the potentiation window in each bin. Lines show the mean across networks; shaded regions indicate 95% confidence intervals.</p> 2026-10-01T18:04:22Z Image Figure 10.1371/journal.pcbi.1014798.g008 https://figshare.com/articles/figure/_p_Long-range_synapses_experience_delayed_spike_synchrony_p_/34049638 CC BY 4.0