2026-10-12T11:21:07Z
https://api.figshare.com/v2/oai
oai:figshare.com:article/34049359
2026-10-01T17:46:38Z
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<p>ITS structure and diagnostic alleles.</p>
Egie E. Enabuele (25158001)
Roy N. Platt II (13783184)
Ehizogie E. Adeyemi (25158004)
Martins S. O. Aisien (25158007)
Oluwaremilekun G. Ajakaye (4243018)
Mahmud U. Ali (25158010)
Ebube C. Amaechi (25158013)
Tolulope E. Atalabi (25158016)
Timothy Auta (25158019)
Oluwaseun B. Awosolu (25158022)
Adamu G. Dagona (25158025)
Omoyemwen Edo-Taiwo (25158028)
Chika P. Ejikeugwu (25158031)
Christopher Igbeneghu (25158034)
Victor S. Njom (10928747)
Marian Onwude-Agbugui (25158037)
Mary-Kate N. Orji (25158040)
Funso O. P. Oyinloye (25158043)
Esther Oyemade (25158046)
Habibat J. Ozemoka (25158049)
Christopher R. Pam (25158052)
Uchenna I. Ugah (25158055)
Jenna M. Hulke (25158058)
Grace A. Arya (25158061)
Timothy J. C. Anderson (7548590)
Physical Sciences not elsewhere classified
Microbiology
Genetics
Environmental Sciences not elsewhere classified
Ecology
Biological Sciences not elsewhere classified
Cancer
Infectious Diseases
tight cluster regardless
internal transcribed spacer
genome sequencing revealed
approach requires reinterpretation
also genome sequenced
14 nigerian locations
schistosomes containing 50
early generation hybrids
documenting zoonotic infection
detecting zoonotic infection
div >< p
suggesting zoonotic infection
132 parasites isolated
schistosoma haematobium </
livestock schistosome markers
bovis cox1 </
zoonotic infection
livestock schistosomes
schistosoma </
zoonotic infections
schistosome epidemiology
recent hybrids
bovis </
haematobium </
cox1 </
livestock parasites
livestock counterparts
curassoni </
cox </
wide ancestry
well differentiated
used approaches
typically inferred
southern nigeria
results demonstrate
northern nigeria
modest levels
misleading inference
low levels
human urine
<p><b>(A)</b> The internal transcribed spacer (ITS) is a region within the 45S rDNA operon that separates the 18S and 28S small and large ribosomal subunits. The ITS locus used for species identification in schistosomes spans the ITS1, 5.8S, and ITS2 regions. Five diagnostic sites within this locus are commonly used to classify schistosomes to the species level. <b>(B)</b> Sanger chromatograms at diagnostic positions along the ITS locus. Dual peaks at positions 704, 759, 809, and 879 indicate heterozygous alleles containing both <i>S. curassoni</i> and <i>S. haematobium</i> variants.</p>
2026-10-01T17:46:27Z
Image
Figure
10.1371/journal.ppat.1014625.g001
https://figshare.com/articles/figure/_p_ITS_structure_and_diagnostic_alleles_p_/34049359
CC BY 4.0