2026-10-11T23:26:21Z https://api.figshare.com/v2/oai

oai:figshare.com:article/34048877 2026-10-01T17:37:57Z category_12 category_21 category_106 portal_5 item_type_1 month_year_10_2026

<p>Validation sample size and the precision limit for current prevalence.</p> Han Liu (288039) Cell Biology Biotechnology Science Policy effective sample size distribution invitation targets based rule selected 15 %, compared validation resources jointly original validation sample negative validation samples negative validation participants 247 conditional invitations predictive width attainment conditional planning selected comparable assumed cost specified relative costs overplanning loss ratio 794 screening invitations positive planning proportion joint parameter uncertainty validation planning 708 invitations width floor separate cost parameter uncertainty positive proportion xlink "> theoretic recruitment survey design study examined point half planning current known within illustrative underplanning depression surveys data performance budget retained <p>The curve shows the minimum attainable 95% confidence-interval half-width for current reference-standard prevalence as the reference-negative validation sample increases. The reference-positive validation sample remains fixed at 28. The horizontal line is the prespecified 0.020 target; π₀ = 28/1,045 and Se = Sp = 0.86.</p> 2026-10-01T17:37:52Z Image Figure 10.1371/journal.pone.0359867.g002 https://figshare.com/articles/figure/_p_Validation_sample_size_and_the_precision_limit_for_current_prevalence_p_/34048877 CC BY 4.0