2026-10-06T23:45:45Z https://api.figshare.com/v2/oai

oai:figshare.com:article/34048243 2026-10-01T17:31:22Z category_4 category_13 category_14 category_24 category_61 category_62 portal_5 item_type_1 month_year_10_2026

<p>SOD activity in <i>D. melanogaster.</i></p> Mohamed Lotfy (18599184) Fatema Al Sawai (25157749) Dhoha Alyammahi (25157752) Biduth Kundu (18599205) Biochemistry Genetics Molecular Biology Evolutionary Biology Developmental Biology Marine Biology xlink "> flies increased trehalose levels excess dietary sugar functional locomotor impairment drosophila melanogaster </ induced metabolic dysfunction antioxidant enzyme activities impaired locomotor performance gene expression levels antioxidant enzyme activity 15 mm ). xlink "> high without metformin treatment related gene expression metformin modulates survival drosophila </ locomotor performance locomotor activity gene expression t2dm ). 15 %), related genes metabolic parameters metabolic disorders treatment groups treated groups tractable model studying diet study investigates quantified relative molecular effects modulatory effects major contributor including improvements gst ), findings support diabetes model changes within carbohydrate imbalance alterations relative also associated 5 mm 10 days <p>Bar graph showing mean SOD activity normalized to total protein (± SD) across NC, S5, S15, SM5, and SM15 groups. Both sucrose-only groups showed significantly reduced SOD activity relative to NC. SM5 showed a non-significant increase relative to S5, whereas SM15 showed a significant increase relative to S15, although activity remained below NC. Data represent three independent biological experiments. *P < 0.05 versus NC; #P < 0.05 for S5 versus SM5 or S15 versus SM15, as applicable.</p> 2026-10-01T17:31:03Z Image Figure 10.1371/journal.pone.0359638.g005 https://figshare.com/articles/figure/_p_SOD_activity_in_i_D_melanogaster_i_p_/34048243 CC BY 4.0