2026-10-13T14:27:28Z
https://api.figshare.com/v2/oai
oai:figshare.com:article/34048238
2026-10-01T17:31:21Z
category_4
category_7
category_8
category_12
category_14
category_16
category_21
category_873
category_46
category_64
category_132
portal_5
item_type_1
month_year_10_2026
<p>Histopathological examination of splenic tissue stained with hematoxylin and eosin.</p>
Naim Gheymoumi (25157753)
Sevda Shayesteh (25157756)
Fatemeh Sharifi (3496619)
Marziyeh Amiri-Andebili (25157759)
Hediyeh Gheymoumi (25157762)
Biochemistry
Medicine
Microbiology
Cell Biology
Molecular Biology
Physiology
Biotechnology
Chemical Sciences not elsewhere classified
Immunology
Cancer
Infectious Diseases
potential immunometabolic modulator
following ova sensitization
endogenous tryptophan metabolite
elevated serum ige
aryl hydrocarbon receptor
serum inflammatory markers
including increased sneezing
mucosal immune regulation
systemic inflammatory mediators
study investigated kyna
findings support kyna
marked inflammatory changes
xlink "> rats
local regulatory cytokines
ar remain unclear
systemic effects comparable
ahr signaling contributes
xlink ">
regulatory cytokines
systemic anti
inflammatory infiltration
histopathological changes
inflammatory effects
cytokine regulation
associated regulation
ahr signaling
kyna ),
splenic tissues
splenic histopathology
kynurenic acid
indicating involvement
immunomodulatory properties
greater improvement
epithelial damage
behavioral responses
associated proteins
<p>(Red pulp: RP; white pulp: WP; periarteriolar lymphocyte sheath: PALS; lymphoid follicles: LF; marginal zones: MZ; abnormal architecture: asterisk). The AR group demonstrated disruption of normal splenic architecture compared with controls. KYNA partially restored splenic organization, whereas desloratadine showed limited improvement. Samples include (A) Control, (B) AR, (C) Al(OH)<sub>3</sub>, (D) KYNA, and (E) desloratadine groups. All images were obtained at ×40 magnification.</p>
2026-10-01T17:31:10Z
Image
Figure
10.1371/journal.pone.0359624.g005
https://figshare.com/articles/figure/_p_Histopathological_examination_of_splenic_tissue_stained_with_hematoxylin_and_eosin_p_/34048238
CC BY 4.0