2026-10-06T04:21:57Z https://api.figshare.com/v2/oai

oai:figshare.com:article/34045779 2026-10-01T12:42:31Z category_1325 portal_316 item_type_3 month_year_10_2026

Table 1_Cross-sectional analysis of 152 hyperthyroid cats presented for radioactive iodine therapy in South Korea.xlsx Dasom Son (16448105) Yeon Chae (11556277) Taesik Yun (11556280) Hakhyun Kim (11556286) Jae-Cheong Lim (16537080) Byeong-Teck Kang (11556292) Veterinary Anaesthesiology and Intensive Care Asia epidemiology feline hyperthyroidism radioiodine therapy referral patterns Introduction<p>Feline hyperthyroidism is one of the most common endocrinopathies in cats; however, its epidemiological characteristics remain poorly understood in South Korea. Although radioactive iodine therapy (RAIT) is a definitive treatment, studies focusing specifically on cats with hyperthyroidism undergoing RAIT are limited.</p>Methods<p>Medical records of 152 cats with hyperthyroidism presented for RAIT were retrospectively reviewed to describe their epidemiological and clinical features.</p>Results<p>The median age at diagnosis was 12 years, and 30.3% of the cats were diagnosed incidentally. RAIT was usually performed soon after diagnosis, with a median disease duration of 5 months; only 4.6% of cats had a disease duration >2 years. Unilateral thyroid disease was the predominant pattern (50.7%), and severe hyperthyroidism (total thyroxine ≥19.4 μg/dl) was observed in 10.5% of cats. Only 40.1% of cats underwent RAIT following the veterinarian's recommendation, whereas 59.9% of owners sought RAIT independently. Human-licensed or generic methimazole was used more frequently than veterinary-licensed methimazole (84.0 vs. 18.1%). Pruritus occurred more frequently with human-licensed or generic methimazole than with veterinary-licensed methimazole (p = 0.047). All cats were housed indoors. The regional distribution of cases differed from the reported national distribution of owned cats (p = 0.016). No cats originated from Jeju-do, which differed significantly from the mainland regions (p = 0.0004). Longer disease duration was associated with more advanced disease, including higher thyroid hormone levels and scintigraphic activity, increased bilateral involvement, and a higher rate of refractory response to antithyroid drugs (all p ≤ 0.001).</p>Conclusions<p>This is the first study to characterize cats with hyperthyroidism that were presented for RAIT in South Korea. Key findings included an owner-driven pattern of RAIT selection, early use of definitive therapy despite a relatively late diagnosis, predominant use of non-veterinary methimazole formulations, and a higher frequency of pruritus as an adverse effect. These findings contribute to the epidemiological understanding of feline hyperthyroidism and may inform clinical decision-making in South Korea.</p> 2026-10-01T12:42:31Z Dataset Dataset 10.3389/fvets.2026.1906840.s001 https://figshare.com/articles/dataset/Table_1_Cross-sectional_analysis_of_152_hyperthyroid_cats_presented_for_radioactive_iodine_therapy_in_South_Korea_xlsx/34045779 CC BY 4.0