2026-10-12T15:37:18Z https://api.figshare.com/v2/oai

oai:figshare.com:article/34044567 2026-10-01T11:27:29Z category_915 category_16 category_272 category_873 category_39 category_734 category_61 category_69 portal_87 item_type_6 month_year_10_2026

Multifunctional Nanoparticle-Modified Pit and Fissure Sealants with Enhanced Mechanical Strength and Antimicrobial Properties-A Review Awais Khalid (10803347) Pervaiz Ahmad (4386976) Fawad Ali Shah (8613054) Fariha Aman (25156320) Nawshad Muhammad (551478) Physical Sciences not elsewhere classified Physiology Environmental Sciences not elsewhere classified Chemical Sciences not elsewhere classified Ecology Biological Sciences not elsewhere classified Developmental Biology Inorganic Chemistry Nanoparticles inorganic fillers pit and fissure sealants crystal phase mechanical properties antimicrobial properties structure-activity relationships TiO2 anatase rutile hydroxyapatite <p>Dentist-placed pit and fissure sealants prevent biofilm formation on occlusal surfaces. Resin-based and glass ionomer sealants have limited longevity, polymerization shrinkage, and no intrinsic antimicrobial activity. This review examines nanoparticulate inorganic fillers that address these limitations. It evaluates how synthesis conditions, crystallographic phase, particle morphology, and surface chemistry of hydroxyapatite, calcium phosphate, zinc oxide, titanium dioxide, silver, cerium oxide, bioactive glass, and calcium fluoride affect mechanical and cariostatic properties. Crystal phase, preparation route, functionalization, filler content, size, surface area, morphology, and dispersion govern composite performance. Comparative studies support rational design of next-generation cariostatic sealants and distinguish established relationships from hypotheses.</p> 2026-10-01T11:27:29Z Text Journal contribution 10.6084/m9.figshare.34044567.v1 https://figshare.com/articles/journal_contribution/Multifunctional_Nanoparticle-Modified_Pit_and_Fissure_Sealants_with_Enhanced_Mechanical_Strength_and_Antimicrobial_Properties-A_Review/34044567 CC BY 4.0