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        <datestamp>2026-10-01T09:59:33Z</datestamp>
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          <dc:title>One Axis for Diverse Particles: Polyphosphate Predicts and Controls Nanoparticle-Induced Antibiotic Persistence in &lt;i&gt;Escherichia col&lt;/i&gt;&lt;i&gt;i&lt;/i&gt;</dc:title>
          <dc:creator>Rui Sun (19535113)</dc:creator>
          <dc:subject>Bacteriology</dc:subject>
          <dc:subject>Nanomaterials</dc:subject>
          <dc:subject>Inorganic polyphosphate (polyP)</dc:subject>
          <dc:subject>Bacterial persistence</dc:subject>
          <dc:subject>Nanoparticles -- Toxicology</dc:subject>
          <dc:description>&lt;p dir="ltr"&gt;Intermittent exposure of &lt;i&gt;Escherichia coli&lt;/i&gt; to 10× MIC AgNPs induces the formation of persister cells. This induction of persistence is driven by intracellular accumulation of polyphosphate (polyP). Moreover, a range of distinct nanomaterials, including CuNPs, ZnO NPs, Fe&lt;sub&gt;3&lt;/sub&gt;O&lt;sub&gt;4&lt;/sub&gt; NPs, CeO&lt;sub&gt;2&lt;/sub&gt; NPs, and SiO&lt;sub&gt;2&lt;/sub&gt; NPs, were also found to trigger polyP-dependent persister formation. Importantly, intracellular polyP levels can serve as a predictive indicator of the proportion of persister cells induced by nanomaterial exposure.&lt;/p&gt;</dc:description>
          <dc:date>2026-10-01T09:59:33Z</dc:date>
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