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        <datestamp>2026-10-01T08:27:46Z</datestamp>
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          <dc:title>Postoperative pneumocephalus in unilateral chronic subdural hematoma and its correlation with recurrence: a retrospective single-center study</dc:title>
          <dc:creator>Adrian Liebert (25155375)</dc:creator>
          <dc:creator>Thomas Eibl (25155378)</dc:creator>
          <dc:creator>Leonard Ritter (25155381)</dc:creator>
          <dc:creator>Karl-Michael Schebesch (9676775)</dc:creator>
          <dc:subject>Medicine</dc:subject>
          <dc:subject>Cell Biology</dc:subject>
          <dc:subject>Genetics</dc:subject>
          <dc:subject>Physiology</dc:subject>
          <dc:subject>Biological Sciences not elsewhere classified</dc:subject>
          <dc:subject>Developmental Biology</dc:subject>
          <dc:subject>Science Policy</dc:subject>
          <dc:subject>Chronic subdural hematoma</dc:subject>
          <dc:subject>subdural air</dc:subject>
          <dc:subject>pneumocephalus</dc:subject>
          <dc:subject>recurrence</dc:subject>
          <dc:subject>hematoma volume</dc:subject>
          <dc:description>&lt;p&gt;Pneumocephalus emerged as a risk factor for recurrence of chronic subdural hematoma (CSDH). However, data on volumetric assessment of subdural air (SA), its risk factors, and correlation with recurrence remain limited.&lt;/p&gt; &lt;p&gt;We retrospectively included patients with unilateral CSDH who underwent surgery. Three analyses were performed: (1) comparison of absolute versus relative SA to preoperative hematoma volume (HV) for predicting recurrence; (2) evaluation of the relationship between SA and recurrence using regression and stratification into four SA-volume subgroups; (3) identification of risk factors for pneumocephalus.&lt;/p&gt; &lt;p&gt;Recurrence was defined as symptomatic re-accumulation of CSDH requiring re-surgery within the first three months of surgery.&lt;/p&gt; &lt;p&gt;142 patients were included. Absolute SA demonstrated a stronger correlation with recurrence, with a cut-off value of 6.95 ml. Each additional 1 ml of SA was associated with a 4.3% increase in the odds of recurrence, and rates ranged from 12.4% in patients (&lt;7 ml) to 45% (&gt;21 ml) (&lt;i&gt;p&lt;/i&gt; &lt; 0.001). Patients with ≥7 ml of SA were older (&lt;i&gt;p&lt;/i&gt; = 0.04), more frequently had hemispheric hematomas (&lt;i&gt;p&lt;/i&gt; = 0.02), and exhibited greater mass effect, reflected by width, HV, and midline shift (all &lt;i&gt;p&lt;/i&gt; &lt; 0.001). Multivariate analysis and ROC-analysis revealed preoperative HV ≥ 105.5 ml as a relevant parameter of increased SA (&lt;i&gt;p&lt;/i&gt; &lt; 0.001).&lt;/p&gt; &lt;p&gt;Preoperative HV demonstrated strongest relation to elevated postoperative SA. Absolute postoperative SA correlates better with recurrence. Patients with ≤6.95 ml of SA have a lower recurrence risk, whereas higher volumes are associated with progressively increased recurrence.&lt;/p&gt;</dc:description>
          <dc:date>2026-10-01T08:27:46Z</dc:date>
          <dc:type>Text</dc:type>
          <dc:type>Journal contribution</dc:type>
          <dc:identifier>10.6084/m9.figshare.34041552.v1</dc:identifier>
          <dc:relation>https://figshare.com/articles/journal_contribution/Postoperative_pneumocephalus_in_unilateral_chronic_subdural_hematoma_and_its_correlation_with_recurrence_a_retrospective_single-center_study/34041552</dc:relation>
          <dc:rights>CC BY 4.0</dc:rights>
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