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oai:figshare.com:article/34041000 2026-10-01T07:22:37Z category_37339 category_37375 portal_1012 item_type_6 month_year_10_2026

Supp Figs S11-S16 from Asynchronous Evolution of Epithelium and Stroma Differentiates Precursor Lesions from Pancreatic Cancer Ahmed M. Elhossiny (15560567) Padma Kadiyala (15053314) Jude O. Okoye (24510707) Harrison L. Hiraki (25154628) Megan C. Procario (24510704) Thejaswini Giridharan (24327989) Hannah R. Watkoske (15560594) Mariana Tannus Ruckert (25154631) Jiayue Wang (25154634) Brian D. Griffith (15560576) Alexander W. Bray (25154637) Jamie N. Mills (25154640) Carlos E. Espinoza (15560603) Jörg Zeller (25154643) Nicole Peterson (15560618) Filip Bednar (15034667) Yaqing Zhang (15110513) Arvind Rao (14855188) Costas A. Lyssiotis (14855185) Julianne M. Szczepanski (22939613) Jiaqi Shi (14935082) Atul Deshpande (19426465) Anirban Maitra (15122821) Elana J. Fertig (9520792) Eileen S. Carpenter (15560564) Timothy L. Frankel (15560627) Marina Pasca di Magliano (14855191) Cancer Methods and Technology Single Cell Technologies Single-cell RNA Sequencing (scRNA-seq) <p>Supplementary Figure S11. A. High magnification hematoxylin and eosin (H&E) image with the Visium spots overlaid, showing adjacency of Fibro1 and Adipose domains, colored by the annotated spatial domain. Supplementary Figure S12. A. Spatially-informed clustering results from donor samples validation dataset, showing 9 different spatial domains based on gene expression from all cells in the spot. Supplementary Figure S13. A. Violin plot showing the Fibro2 and Fibro3 signature score in the fibroblast spatial domain of the donor samples validation dataset. Supplementary Figure S14. A. UMAP representation of integrated Xenium samples from Fiorini et al. (81) dataset, colored by annotated cell type. Supplementary Figure S15. A. Dot plot showing the expression of WNT ligands, receptors and downstream targets in different spatial domains from spatial transcriptomics data. Supplementary Figure S16. A. UMAP representation of scRNAseq data from the mono- and co-culture experiment.</p> 2026-10-01T00:00:00Z Text Journal contribution 10.1158/2159-8290.34041000 https://figshare.com/articles/journal_contribution/Supp_Figs_S11-S16_from_Asynchronous_Evolution_of_Epithelium_and_Stroma_Differentiates_Precursor_Lesions_from_Pancreatic_Cancer/34041000 CC BY