2026-10-12T01:45:09Z https://api.figshare.com/v2/oai

oai:figshare.com:article/34040553 2026-10-01T06:54:07Z category_4 category_146 category_7 category_14 category_21 category_873 category_734 category_62 portal_87 item_type_6 month_year_10_2026

Comparative biomedical and photocatalytic efficacy of <i>Malvastrum coromandelianum</i> (L.) aqueous extract-assisted green synthesized zinc oxide and copper oxide nanoparticles Shumaila Iqbal (22238550) Naveed Ahmad (2570878) Abu Bakar Siddique (10232803) Azhar Abbas (506036) Syed Nasir Abbas Bukhari (9696910) Hassan Ejaz (14115173) Omar A. Alsaidan (21372107) Biochemistry Space Science Medicine Molecular Biology Biotechnology Chemical Sciences not elsewhere classified Biological Sciences not elsewhere classified Marine Biology Antibacterial activity anti-inflammatory potential of NPs antioxidant assays biogenic synthesis of metal nanoparticles photodegradation of azo dyes <p>This study presents the biogenic synthesis of CuO nanoparticles (NPs) and ZnO NPs using aqueous leaf extract of <i>Malvastrum coromandelianum</i> as a green reducing and stabilizing agent. The synthesized NPs were characterized by UV–vis, PXRD, FTIR, ZP, DLS, SEM, TEM, BET, and EDX. The photocatalytic potential of the synthesized NPs was evaluated by degrading methylene blue (MB) and methyl orange (MO) dyes under sunlight. The synthesized ZnO and CuO NPs also exhibited remarkable biomedical applications by showing strain-specific antibacterial activity and substantial antioxidant properties assessed by DPPH, FRAP, and TPC assays. CuO NPs were more effective against <i>L. monocytogenes</i> and <i>S. enterica</i>, with minimum inhibitory concentration (MIC) values of 15 ± 0.85 and 13 ± 1.75 mg/mL, respectively, while ZnO NPs targeted <i>P. aeruginosa</i> more efficiently, with an MIC value of 12 ± 1.9 mg/mL. CuO NPs have also demonstrated better antioxidant efficacy than ZnO NPs, assessed by DPPH, FRAP, and TPC assays. All these applications highlighted the photocatalytic and biomedical efficacy of green-synthesized CuO NPs and ZnO NPs.</p> <p>Although green synthesis of ZnO NPs and CuO NPs using various plant extracts has been widely explored, but the direct comparisons of structure–property relationships and performance have not been conducted due to differing synthesis conditions. This work uniquely employed <i>Malvastrum coromandelianum</i> (L.) extract as a single phytochemical system to synthesize both ZnO and CuO NPs under comparable conditions, enabling a systematic, direct comparison of their structure–property relationships and performance in terms of photocatalytic, antibacterial, antioxidant, and anti-inflammatory activities.</p> 2026-10-01T06:54:07Z Text Journal contribution 10.6084/m9.figshare.34040553.v1 https://figshare.com/articles/journal_contribution/Comparative_biomedical_and_photocatalytic_efficacy_of_i_Malvastrum_coromandelianum_i_L_aqueous_extract-assisted_green_synthesized_zinc_oxide_and_copper_oxide_nanoparticles/34040553 CC BY 4.0