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Additional file 4 of Opsoclonus revealing underlying multiple system atrophy: a case report Hiromi Kawano (25153452) Shotaro Sakimura (25153455) Ken Yamaura (846052) Space Science Medicine Cell Biology Genetics Neuroscience Physiology Environmental Sciences not elsewhere classified Multiple system atrophy Opsoclonus Delayed emergence General anesthesia Fentanyl Additional file 4: Figure S2. Simulated fentanyl concentration profile. Estimated fentanyl plasma and effect-site concentrations over time, simulated using AnestAssist™ pharmacokinetic/pharmacodynamic software based on the Shafer pharmacokinetic model, are shown. The estimated effect-site concentration at the onset of abnormal eye movements was approximately 0.48 ng/mL. Values are model-based estimates and do not represent measured plasma concentrations. PK, pharmacokinetic; Pt, patient. 2026-07-03T05:00:00Z Text Presentation 10.6084/m9.figshare.34040373.v1 https://figshare.com/articles/presentation/Additional_file_4_of_Opsoclonus_revealing_underlying_multiple_system_atrophy_a_case_report/34040373 CC BY