2026-10-14T07:39:03Z https://api.figshare.com/v2/oai

oai:figshare.com:article/34038885 2026-10-01T04:43:30Z category_393 portal_316 item_type_3 month_year_10_2026

Data Sheet 1_Construction and validation of a frailty screening model for older adults with cataract: a cross-sectional study.docx Xingdong Cheng (4623748) Heting Liang (19654318) Qingyun Mao (2116105) Yumeng Zhang (3115050) Shaoting Yang (15197055) Honghong Wen (22293862) Xiaoli Yuan (359671) Foetal Development and Medicine associated factors cataract frailty older adults risk assessment model Objective<p>To develop and internally validate a frailty screening model for older adults with cataract that relies only on information already collected during routine ophthalmology outpatient assessment.</p>Methods<p>In this cross-sectional study, 516 patients aged ≥ 60 years were enrolled and randomly divided into training (n = 361) and internal validation (n = 155) sets. Frailty was defined by the FRAIL scale, with non-frail and pre-frail categories combined for the primary binary analysis. Univariate screening was followed by multivariable binary logistic regression, with LASSO and a 5,000-resample bootstrap of the full development procedure as stability checks.</p>Results<p>The frailty detection rate was 29.07%. Five factors were independently associated with frailty: advanced age, IADL impairment, poor self-rated health, depression, and history of falls. Discrimination was good (training AUC 0.841, 95% CI 0.796–0.887; validation AUC 0.816, 95% CI 0.745–0.888), the optimism-corrected C-statistic was 0.810 (95% CI 0.780–0.841), and calibration was acceptable (validation Brier score 0.1553). Decision curve analysis showed positive net benefit across a broad threshold range. Lowering the operating point from the Youden cutoff (0.463; sensitivity 57.8%, specificity 86.4%) to 0.181 raised validation sensitivity to 86.7% with a negative predictive value of 92.1%.</p>Conclusions<p>Because all five predictors are already recorded during routine cataract assessment, the model offers an opportunistic, zero-burden triage step for identifying concurrent frailty and prompting comprehensive geriatric assessment. External validation and comparison with the FRAIL scale are required.</p> 2026-10-01T04:43:30Z Dataset Dataset 10.3389/fmed.2026.1934999 https://figshare.com/articles/dataset/Data_Sheet_1_Construction_and_validation_of_a_frailty_screening_model_for_older_adults_with_cataract_a_cross-sectional_study_docx/34038885 CC BY 4.0