2026-10-06T04:19:00Z https://api.figshare.com/v2/oai

oai:figshare.com:article/34038270 2026-10-01T04:32:13Z category_363 portal_316 item_type_3 month_year_10_2026

Table 1_Temporal synchronization during bilateral foot-tapping and its relationship with gait disturbance in patients with Parkinson’s disease.xlsx Atsuki Numata (20638964) Yasuo Terao (337735) Naohiko Togashi (25152054) Kazuko Hasegawa (180560) Kenichi Sugawara (131735) Yoshikazu Ugawa (337741) Toshiaki Furubayashi (337738) Neurology and Neuromuscular Diseases dysrhythmia freezing of gait gait rehabilitation Parkinson’s disease synchronized tapping temporal process Objective<p>Previous studies using finger-tapping tasks have shown that patients with Parkinson’s disease (PD) exhibit a deficit of temporal processing linked to gait disturbance. In this study, we aimed to investigate abnormalities in lower-limb rhythmic control and their association with freezing of gait in PD using a bilateral foot-tapping task.</p>Methods<p>Fifteen patients with PD and 25 healthy controls performed foot-tapping tasks synchronized with auditory tones at fixed intervals (500–2,400 ms). The tasks included unilateral and bilateral foot-tapping, with bilateral movements performed either in-phase (simultaneous) or antiphase (alternating). Data on synchronizing tapping error and inter-tap interval variability were analyzed and correlated with scores from clinical assessments, including the Unified Parkinson’s Disease Rating Scale and Freezing of Gait Questionnaire.</p>Results<p>Patients with PD showed greater negative synchronizing tapping error (negative asynchrony) and higher inter-tap interval variability than did controls, especially in antiphase condition. Exploratory within-PD-group analyses suggested associations between clinical severity and abnormalities in bilateral foot-tapping performance.</p>Conclusion<p>These findings indicate altered temporal accuracy and stability of rhythmic lower-limb movements in PD, particularly during bilateral antiphase foot-tapping. Bilateral foot-tapping measures may help characterize lower-limb timing deficits that are relevant to gait rehabilitation in PD.</p> 2026-10-01T04:32:13Z Dataset Dataset 10.3389/fneur.2026.1860090.s001 https://figshare.com/articles/dataset/Table_1_Temporal_synchronization_during_bilateral_foot-tapping_and_its_relationship_with_gait_disturbance_in_patients_with_Parkinson_s_disease_xlsx/34038270 CC BY 4.0