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oai:figshare.com:article/34037154 2026-09-30T23:05:47Z category_1 category_4 category_14 category_873 category_734 category_106 category_122 category_132 category_135 portal_63 item_type_6 month_year_09_2026

Electrochemical Divergent Transformation of Flavonoids to Dihydroflavonols and 3‑Iodoflavones Yi Sun (118759) Changsheng Qin (14510895) Xinyue Li (628935) Jiawei Guo (1488853) Zhihua Zhang (16756) Jingfang Wang (523664) Chenxu Li (5404568) Jierong Liu (25146954) Lanyu Yang (25146957) Shoucai Wang (162933) Fanghua Ji (1589839) Guangbin Jiang (4370827) Biophysics Biochemistry Molecular Biology Chemical Sciences not elsewhere classified Biological Sciences not elsewhere classified Science Policy Mental Health Infectious Diseases Computational Biology mechanistic studies identify key reaction intermediates featuring tunable selectivity electrochemical divergent transformation 3 ‑ iodoflavones undivided cell simply switching room temperature protocol operates operational simplicity metal catalysts external oxidants controllable synthesis We report an electrochemically regulated divergent C–H functionalization of flavonoids that enables the controllable synthesis of dihydroflavonols or 3-iodoflavones from the same substrates by simply switching the electrolyte and solvent. This protocol operates in an undivided cell at room temperature under air, featuring tunable selectivity, no need for external oxidants or transition-metal catalysts, and operational simplicity. Mechanistic studies identify the key reaction intermediates. 2026-09-30T00:00:00Z Text Journal contribution 10.1021/acs.orglett.6c03424.s001 https://figshare.com/articles/journal_contribution/Electrochemical_Divergent_Transformation_of_Flavonoids_to_Dihydroflavonols_and_3_Iodoflavones/34037154 CC BY-NC 4.0