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        <identifier>oai:figshare.com:article/34036904</identifier>
        <datestamp>2026-09-30T20:38:12Z</datestamp>
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          <dc:title>Current status of 3D-printed human ossicles: a systematic review</dc:title>
          <dc:creator>Elissa Suleiman (25146221)</dc:creator>
          <dc:creator>Steven Arild Wuyts Andersen (7874462)</dc:creator>
          <dc:creator>Adam Omari (25146224)</dc:creator>
          <dc:subject>Medicine</dc:subject>
          <dc:subject>Cell Biology</dc:subject>
          <dc:subject>Environmental Sciences not elsewhere classified</dc:subject>
          <dc:subject>Science Policy</dc:subject>
          <dc:subject>Information Systems not elsewhere classified</dc:subject>
          <dc:subject>Temporal bone</dc:subject>
          <dc:subject>printing</dc:subject>
          <dc:subject>three-dimensional</dc:subject>
          <dc:subject>ear ossicles</dc:subject>
          <dc:subject>middle ear</dc:subject>
          <dc:description>&lt;p&gt;Three-dimensional (3D) printed ossicle models may be useful in education and clinical practice, but accurate replication remains challenging.&lt;/p&gt; &lt;p&gt;To systematically review 3D-printed ossicles to map replication methods, factors influencing accuracy, and suggest needed innovations for higher accuracy.&lt;/p&gt; &lt;p&gt;PubMed, Embase, Scopus, and Web of Science were searched from inception through June 2025. Two reviewers independently screened for final inclusion. Data on imaging, segmentation, 3D-printing-technology, materials, and post-processing were extracted. Educational studies were appraised using the Medical Education Research Study Quality Instrument. A panel of otosurgeons rated ossicle images for realism and visualization.&lt;/p&gt; &lt;p&gt;Sixty-five studies were included. Most models embedded ossicles in healthy temporal-bones (&lt;i&gt;n&lt;/i&gt; = 46), with fewer pathological (&lt;i&gt;n&lt;/i&gt; = 6) or stand-alone models (&lt;i&gt;n&lt;/i&gt; = 13). Stapes was often absent or poorly reproduced, whereas malleus and incus were usually recognizable. Higher realism was associated with micro-CT or cone-beam-CT combined with stereolithography or PolyJet-printing. These photopolymer-based technologies allowed ossicle mobility in selected models. However, reporting of replication methods and anatomical accuracy was often limited, constraining deeper comparison between studies.&lt;/p&gt; &lt;p&gt;Accurate ossicle replication is emerging but depends on optimization of imaging, processing, and 3D-printing. Standardized reporting is needed to improve comparison between methods and support use in training and reconstruction.&lt;/p&gt;</dc:description>
          <dc:date>2026-09-30T20:38:12Z</dc:date>
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          <dc:identifier>10.6084/m9.figshare.34036904.v1</dc:identifier>
          <dc:relation>https://figshare.com/articles/journal_contribution/Current_status_of_3D-printed_human_ossicles_a_systematic_review/34036904</dc:relation>
          <dc:rights>CC BY 4.0</dc:rights>
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