2026-10-09T17:40:56Z https://api.figshare.com/v2/oai

oai:figshare.com:article/34035731 2026-09-30T17:40:04Z category_7 category_19 category_21 category_734 category_106 category_132 portal_5 item_type_1 month_year_09_2026

<p>Representative drugs and drug classes potentially affected by climate change.</p> Pono Pono (25145034) Alan M. Jones (52267) Medicine Pharmacology Biotechnology Biological Sciences not elsewhere classified Science Policy Infectious Diseases potentially reducing efficacy emerging evidence shows challenges remains fragmented affect drug stability adverse drug events review synthesises evidence particularly extreme heat climate &# 8209 assessing potential implications altering pharmaceutical formulations pharmaceuticals </ p increasing disease burden diseases affecting cardiovascular disease burden pharmaceutical treatments review found review finds drug safety urgent need threatening access thermoregulatory system therapeutic response support resilient respiratory systems related stressors potential impact patient responses older adults integrated research increased morbidity human health high temperature health systems current knowledge climate change chronic diseases <p>Climate-related stressors may influence the efficacy, safety, pharmacokinetics, and pharmaceutical formulations of medications used across different therapeutic areas. These include antidepressants, antipsychotics, anticonvulsants, antihypertensives, diuretics, and immunosuppressants. Abbreviations: TCAs: tricyclic antidepressants; MAOs: monoamine oxidase inhibitors; SSRIs: selective serotonin reuptake inhibitors; SNRIs: serotonin-norepinephrine reuptake inhibitors.</p> 2026-09-30T17:40:01Z Image Figure 10.1371/journal.pclm.0001068.g003 https://figshare.com/articles/figure/_p_Representative_drugs_and_drug_classes_potentially_affected_by_climate_change_p_/34035731 CC BY 4.0