2026-10-13T20:09:43Z
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2026-09-30T17:26:47Z
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<p>Effects of α-syn preparation infusion in the SNpc of aged mice for up to 5 weeks.</p>
Noelle Callizot (5660677)
Georgia Culley (15148575)
Grace Flower (25145065)
Laura Rouvière (16400955)
Véronique De Conto (25145068)
Alexandre Wojcinski (6340172)
Catherine Botto (25145071)
Cecilia Estrella (1618609)
Alexandre Henriques (359791)
Philippe Verwaerde (1618624)
Biochemistry
Cell Biology
Genetics
Molecular Biology
Neuroscience
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Cancer
promising therapeutic approach
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pathohistological hallmarks
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<p>IHC analysis shows the total number of TH(+) neurons (A), α-syn accumulation in TH(+) neurons (B) and the number of Iba1(+) microglia in SNpc (C) expressed as % of sham. Raw values for sham (i.e., 100%); TH(+) neurons = 70 ± 2.0; α-syn area/TH(+) neuron = 1229 ± 47 µm<sup>2</sup>; Iba1(+) cells = 249 ± 7.1. Each bar represents the mean ± SEM, one-way ANOVA followed by Fisher’s test. <sup>#</sup>p < 0.05, <sup>##</sup>p < 0.01, <sup>###</sup>p < 0.001 or <sup>####</sup>p < 0.0001 from sham (n = 7 mice / group).</p> <p>(TIF)</p>
2026-09-30T17:26:42Z
Image
Figure
10.1371/journal.pone.0359269.s004
https://figshare.com/articles/figure/_p_Effects_of_-syn_preparation_infusion_in_the_SNpc_of_aged_mice_for_up_to_5_weeks_p_/34034659
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