2026-10-11T21:18:32Z
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oai:figshare.com:article/34034650
2026-09-30T17:26:44Z
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<p>Segmentation analysis for immunocytochemistry images from <i>in vitro</i> models of PD.</p>
Noelle Callizot (5660677)
Georgia Culley (15148575)
Grace Flower (25145065)
Laura Rouvière (16400955)
Véronique De Conto (25145068)
Alexandre Wojcinski (6340172)
Catherine Botto (25145071)
Cecilia Estrella (1618609)
Alexandre Henriques (359791)
Philippe Verwaerde (1618624)
Biochemistry
Cell Biology
Genetics
Molecular Biology
Neuroscience
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Cancer
promising therapeutic approach
lewy bodies ).
several lysosomal enzymes
restoring lysosomal homeostasis
lysosomal availability depend
like models (<
parkinson &# 8217
maintaining lysosomal function
div >< p
neuroprotective effects involve
several parkinson ’
lysosomal function
neuroprotective effects
lysosomal system
lysosomal dysfunction
parkinson ’
neuroprotective action
disease models
vivo </
vitro </
ultimately supporting
prone proteins
pathohistological hallmarks
mitochondrial injury
genetic connections
endoplasmic reticulum
dopaminergic neurons
direct link
clinical development
<p>Cell segmentation to separate the nuclear and cytoplasmic compartments which were then used to assess the area of markers, e.g., within the cytoplasmic compartment (A). Neurite segmentation in TH(+) neurons (red), observed in green (B). PSD95(+) puncta (green) in TH(+) neurites (red) (C).</p> <p>(TIF)</p>
2026-09-30T17:26:42Z
Image
Figure
10.1371/journal.pone.0359269.s001
https://figshare.com/articles/figure/_p_Segmentation_analysis_for_immunocytochemistry_images_from_i_in_vitro_i_models_of_PD_p_/34034650
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