2026-10-09T08:50:25Z https://api.figshare.com/v2/oai

oai:figshare.com:article/34034046 2026-09-30T16:58:35Z category_24292 category_24316 item_type_2 month_year_09_2026

Negative geotaxis assay videos examining Centrocortin-dependent locomotor function in <i>Drosophila melanogaster</i> Temitope Adebambo (17132344) Lerit (9187178) Developmental genetics (incl. sex determination) Neurogenetics Centrocortin; Cen Drosophila melanogaster Negative geotaxis assay climbing assay locomotor behavior Locomotor functions motor performance Behavioral genetics neural development neuronal function; mushroom body video recordings <p dir="ltr">This video collection accompanies research investigating the role of Centrocortin (Cen) in neural development and locomotor function in <i>Drosophila melanogaster</i>. The broader study examines how altered Cen expression affects brain development, neural circuit organization, and behavior, with particular interest in mushroom body morphology and function. The movies document adult climbing behavior during the negative geotaxis assay (NGA), which assesses the natural tendency of flies to climb upward against gravity. These recordings provide a behavioral readout for evaluating locomotor performance in the context of Cen genetic manipulation and comparing experimental groups with corresponding controls.</p><p dir="ltr">The collection supports the assessment of locomotor defects associated with Cen dysregulation and complements anatomical and molecular investigations of Cen function in the nervous system. The videos provide a resource for visual inspection and further analysis of climbing behavior</p> 2026-09-30T16:58:35Z Dataset Media 10.6084/m9.figshare.34034046.v1 https://figshare.com/articles/media/Negative_geotaxis_assay_videos_examining_Centrocortin-dependent_locomotor_function_in_i_Drosophila_melanogaster_i_/34034046 CC BY 4.0