2026-10-12T01:04:58Z https://api.figshare.com/v2/oai

oai:figshare.com:article/34032645 2026-09-30T13:35:35Z category_1 category_4 category_7 category_12 category_14 category_16 category_19 category_873 portal_63 item_type_6 month_year_09_2026

Covalent Dimerization of an Aza-5–7–7 Saddle Unlocks Fullerene Recognition toward Both C₆₀ and C₇₀ with Preference for C₇₀ Yujie Ren (2041120) Fengyi Zhao (1449697) Gang Zhang (279544) Weifan Wang (4669081) Biophysics Biochemistry Medicine Cell Biology Molecular Biology Physiology Pharmacology Chemical Sciences not elsewhere classified supramolecular fullerene hosts ray diffraction verifies promising building blocks nonplanar curved π detectable fullerene binding covalently linked aza 1 </ b 70 </ sub 60 </ sub shaped conformation full characterization crystal x covalent dimerization conjugated molecules Nonplanar curved π-conjugated molecules are promising building blocks for supramolecular fullerene hosts, yet negatively curved saddle-based dimeric receptors remain largely underexplored. Herein, we report the synthesis and full characterization of a covalently linked aza-5–7–7 saddle dimer (<b>1</b>). Single-crystal X-ray diffraction verifies its S-shaped conformation with two independent concave cavities. Notably, the monomeric saddle precursor (<b>2</b>) shows no detectable fullerene binding, whereas covalent dimerization unlocks efficient host–guest interactions. NMR and UV–vis titrations reveal that <b>1</b> binds C₇₀ preferentially over C₆₀, and cocrystallization further validates its ability to encapsulate these fullerenes. 2026-09-30T00:00:00Z Text Journal contribution 10.1021/acs.orglett.6c03698.s001 https://figshare.com/articles/journal_contribution/Covalent_Dimerization_of_an_Aza-5_7_7_Saddle_Unlocks_Fullerene_Recognition_toward_Both_C_sub_60_sub_and_C_sub_70_sub_with_Preference_for_C_sub_70_sub_/34032645 CC BY-NC 4.0