2026-10-14T04:20:21Z https://api.figshare.com/v2/oai

oai:figshare.com:article/34030361 2026-09-30T06:40:46Z category_7 category_21 category_734 category_64 category_132 portal_87 item_type_6 month_year_09_2026

Human Papillomavirus (HPV) and Cervical Cancer: An Exploratory Systematic Review of Heterogeneous Evidence on Epidemiology, Vaccination, Screening, and Molecular Advances Seyedeh Shahed Shoarishoar (23151270) Maedeh Seifollahi Marbini (25142222) Medicine Biotechnology Biological Sciences not elsewhere classified Cancer Infectious Diseases Human papillomavirus (HPV) Cervical cancer HPV vaccination HPV genotyping HPV-related malignancies <p>This systematic review evaluated evidence on HPV epidemiology, vaccination, screening, and factors associated with cervical cancer and other HPV-related malignancies. Fourteen heterogeneous studies published between 2010 and 2025 were included. HPV16 remained the most frequently reported genotype, while several studies indicated increasing prevalence of other high-risk genotypes, supporting the potential value of the 9-valent HPV vaccine. Population-based evidence demonstrated reduced cervical cancer incidence among women vaccinated before adolescence. Limited studies also investigated HPV persistence, viral load, microbiome alterations, and vaccine awareness. Considering the small number and diversity of studies, findings should be interpreted cautiously and considered exploratory.</p> 2026-09-30T06:40:46Z Text Journal contribution 10.6084/m9.figshare.34030361.v1 https://figshare.com/articles/journal_contribution/Human_Papillomavirus_HPV_and_Cervical_Cancer_An_Exploratory_Systematic_Review_of_Heterogeneous_Evidence_on_Epidemiology_Vaccination_Screening_and_Molecular_Advances/34030361 CC BY 4.0