2026-10-12T05:56:55Z https://api.figshare.com/v2/oai

oai:figshare.com:article/34027572 2026-09-29T20:11:47Z category_1 category_4 category_146 category_7 category_8 category_21 category_272 category_873 category_734 category_69 portal_63 item_type_6 month_year_09_2026

Poly(Allura Red AC)-Modified Glassy Carbon Electrode: Electropolymerization, Characterization, and Application in Uric Acid Detection Fatma Ağın (25138833) Elif Mollahasanoğlu (25138836) Gökçe Öztürk (25138839) Fatih Erdemir (25138842) Dilek Kul (25138845) Biophysics Biochemistry Space Science Medicine Microbiology Biotechnology Environmental Sciences not elsewhere classified Chemical Sciences not elsewhere classified Biological Sciences not elsewhere classified Inorganic Chemistry surface coverage analysis providing accurate recoveries low detection limits including monomer concentration electrocatalytic sensing interface allura red ac electrochemical impedance spectroscopy dependent electrochemical studies differential pulse voltammetry uric acid detection resulting polymer film uric acid electrochemical properties cyclic voltammetry work provides systematically investigated successfully applied sensor showed linear range ionic strength electrochemical characterization developed methods comprehensive understanding buffer type biological samples 64 nm 47 nm In this study, the electropolymerization, electrochemical characterization, and analytical applicability of a poly(Allura Red AC)-modified glassy carbon electrode were systematically investigated. Electropolymerization parameters, including monomer concentration, buffer type, pH, and ionic strength, were optimized to obtain a stable and electroactive poly(Allura Red AC) film. The resulting polymer film was characterized by cyclic voltammetry, electrochemical impedance spectroscopy, surface coverage analysis, electroactive surface area determination, and pH-dependent electrochemical studies. The modified electrode exhibited enhanced electrocatalytic activity toward the oxidation of uric acid, enabling sensitive voltammetric determination. Under optimized conditions, the sensor showed a linear range of 0.2–40 μM and low detection limits of 7.64 nM and 6.47 nM by cyclic voltammetry and differential pulse voltammetry, respectively. The developed methods were successfully applied to protein-free human serum samples, providing accurate recoveries and no prominent interfering peaks within the uric acid oxidation potential window. This work provides a comprehensive understanding of the formation and electrochemical properties of poly(Allura Red AC) films while demonstrating their applicability as an electrocatalytic sensing interface for sensitive uric acid determination in biological samples. 2026-09-29T00:00:00Z Text Journal contribution 10.1021/acsomega.6c09469.s001 https://figshare.com/articles/journal_contribution/Poly_Allura_Red_AC_-Modified_Glassy_Carbon_Electrode_Electropolymerization_Characterization_and_Application_in_Uric_Acid_Detection/34027572 CC BY-NC 4.0