2026-10-12T19:38:18Z https://api.figshare.com/v2/oai

oai:figshare.com:article/34027385 2026-09-29T19:06:09Z category_1 category_4 category_915 category_12 category_13 category_21 category_64 category_69 category_132 portal_63 item_type_3 month_year_09_2026

Programmable DNA Nanowire Coatings Enable Geometry-Induced Interfacial Control of Bacterial Motility Xiuli Wang (151314) Mengmeng Zhang (1507543) Kui Huang (2334775) Yufeng Zhu (3406496) Qiulan Yang (11086416) Jinyao Liu (1959937) Yang Yang (45629) Biophysics Biochemistry Physical Sciences not elsewhere classified Cell Biology Genetics Biotechnology Cancer Inorganic Chemistry Infectious Diseases tunable surface coverage programmable design parameter nanoscale structural design multiscale interfacial characterization induced interfacial remodeling induced interfacial control distinct structural architectures distinct motility behaviors bacterial motility mechanistic intermediary emergent property dependent divergence cellular dynamics Bacterial motility is an emergent property of dynamic cell–interface interactions, yet the programmable interfacial states governing this behavior remain poorly understood. Here, we engineer bacterial interfaces using DNA nanowire coatings with distinct structural architectures and tunable surface coverage. Two structurally distinct DNA nanowires generate common motility enhancement together with density- and architecture-dependent divergence. Multiscale interfacial characterization further demonstrates that these distinct motility behaviors are associated with geometry-induced interfacial remodeling, identifying programmable interfacial states as the mechanistic intermediary between nanoscale structural design and bacterial motility. These findings establish nanowire geometry as a programmable design parameter for engineering bacterial interfacial states that govern cell–surface interactions and cellular dynamics. 2026-09-29T00:00:00Z Dataset Dataset 10.1021/acsnano.6c14152.s002 https://figshare.com/articles/dataset/Programmable_DNA_Nanowire_Coatings_Enable_Geometry-Induced_Interfacial_Control_of_Bacterial_Motility/34027385 CC BY-NC 4.0