2026-10-13T03:29:06Z
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2026-09-29T17:40:28Z
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<p>Comparative analysis inflammation markers in mice after filovirus infection using the Luminex technology.</p>
Michelle Gellhorn Serra (25138177)
Cornelius Rohde (7356083)
Lucie Sauerhering (6646112)
Lars Meier (9179480)
Lennart Kämper (11608114)
Pauline Neubecker (23778913)
Markus Eickmann (288210)
Alexandra Kupke (4603690)
Stephan Becker (146493)
Anke-Dorothee Werner (16660476)
Medicine
Microbiology
Biotechnology
Ecology
Immunology
Mental Health
Infectious Diseases
Virology
widespread systemic dissemination
viral genome copies
systemic viral dissemination
sup >-/-</ sup
suitable animal models
substantial weight loss
significantly elevated concentrations
div >< p
associated immune responses
post mortem </
key inflammatory features
inflammatory responses described
investigating filovirus pathogenesis
requires preclinical evaluation
pronounced inflammatory response
lethal sudv infection
pronounced changes
preclinical studies
filoviridae </
filovirus infections
filovirus disease
tissue pathology
therapeutic antibodies
tested organs
sudv infection
sudan virus
potential limitation
observed cytokine
multiple cytokines
medical countermeasures
mechanistic basis
infected controls
including antivirals
hematopoietic mediators
following infection
findings characterize
encompassing pro
data support
chemokines compared
chemokine elevations
<p>Values for other publications are approximates/approximate averages. Mean cytokine and chemokine concentrations were estimated by visual inspection of (graphical) data in cited publications (including their supplemental material). Values do not necessarily reflect the exact original measurement but rather should be regarded as approximates and are intended to illustrate relative trends and enable contextual comparisons. Original published (numerical) data, where available, should be considered authoritative. n.s. no upregulation compared to (noninfected) controls. # Reported as comparable to controls; numerical values were not provided.</p> <p>(DOCX)</p>
2026-09-29T17:40:18Z
Text
Journal contribution
10.1371/journal.pone.0347080.s006
https://figshare.com/articles/journal_contribution/_p_Comparative_analysis_inflammation_markers_in_mice_after_filovirus_infection_using_the_Luminex_technology_p_/34027026
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