2026-10-14T10:41:40Z
https://api.figshare.com/v2/oai
oai:figshare.com:article/34026940
2026-09-29T17:38:50Z
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<p>Identified MHC-II antigens of <i>F. tularensis</i> LVS. The epitope region of an antigen is represented by the longest identified peptide sequence and is annotated by the positions in the protein sequence and the number of unique peptides identified (in parenthesis). Part of the sequence is underlined if the peptide selected for synthesis was different from the longest peptide. The names of synthetic peptides and the classification of their reactivity in ELISpot assays are given (n.s.- non-significant, minor or major epitope). Protein name- name of the homolog in <i>F. tularensis</i> SCHU S4 reference proteome (UniProt). <sup>†</sup>Various peptides were synthesized for the epitope region. <sup>‡</sup>Positive control (not identified in our study).</p>
Pavlina Laskova (25138447)
Stanislava Porkertova (25138450)
Ondrej Ballek (11568544)
Lucie Balonova (1392496)
Jana Pavloskova (25138453)
Ales Neuwirth (13913055)
Ivona Pavkova (2339947)
Ivo Fabrik (1849519)
Pavol Lukac (25138456)
Luca Vannucci (14358999)
Dominik Filipp (1849615)
Jiri Stulik (151536)
Marek Link (151527)
Biochemistry
Medicine
Microbiology
Cell Biology
Immunology
Cancer
Infectious Diseases
sup >+</ sup
severe pneumonic form
induced immune responses
identified 57 mhc
div >< p
immunopeptidomics reveals conserved
protective immune response
peptide vaccine containing
fully virulent strains
ensure complete protection
cells following immunization
francisella tularensis </
tularensis </
using immunopeptidomics
based immunopeptidomics
vaccination studies
subsequent screening
significant role
potential role
least 80
ii peptides
human tularemia
highly expressed
fsc200 strain
five epitopes
epitopes proved
early control
dominant epitopes
characterizing antigen
cells playing
cell epitopes
bacterial proteome
23 different
<p>Identified MHC-II antigens of <i>F. tularensis</i> LVS. The epitope region of an antigen is represented by the longest identified peptide sequence and is annotated by the positions in the protein sequence and the number of unique peptides identified (in parenthesis). Part of the sequence is underlined if the peptide selected for synthesis was different from the longest peptide. The names of synthetic peptides and the classification of their reactivity in ELISpot assays are given (n.s.- non-significant, minor or major epitope). Protein name- name of the homolog in <i>F. tularensis</i> SCHU S4 reference proteome (UniProt). <sup>†</sup>Various peptides were synthesized for the epitope region. <sup>‡</sup>Positive control (not identified in our study).</p>
2026-09-29T17:54:09Z
Dataset
Dataset
10.1371/journal.ppat.1014597.t001
https://figshare.com/articles/dataset/_p_Identified_MHC-II_antigens_of_i_F_tularensis_i_LVS_p_/34026940
CC BY 4.0