2026-10-12T01:17:41Z https://api.figshare.com/v2/oai

oai:figshare.com:article/34026726 2026-09-29T17:37:28Z category_1 category_4 category_12 category_13 category_14 category_16 category_19 category_46 category_734 category_811 category_64 category_122 category_132 portal_5 item_type_3 month_year_09_2026

<p>Summary of results for the five best models selected based on the AIC criterion. The table below reports the outcomes of the selection procedure for models 3.1, 3.2, 3.3, 3.4 and 3.5, including the answers to 0–0 and the corresponding statistics for each model (negative log-likelihood, AIC, , number of estimated parameters, convergence status), revealing the existence of two distinct model clusters. Convergence was calculated as the number of runs with a negative log-likelihood value below the minimum negative log-likelihood value plus 0.1.</p> Chloé Weckel (25138386) Juliette Gourdon (25138389) Léo Darrigade (25138392) Vinesh Jugnarain (25138395) Pascale Crépieux (763916) Eric Reiter (7033055) Frédéric Jean-Alphonse (22090247) Stefan Haar (25138398) Romain Yvinec (25138401) Biophysics Biochemistry Cell Biology Genetics Molecular Biology Physiology Pharmacology Immunology Biological Sciences not elsewhere classified Mathematical Sciences not elsewhere classified Cancer Mental Health Infectious Diseases throughput kinetic data often overlooked component model selection method approach thus provides theoretical gpcr models enabling systematic characterization stimulating hormone receptor induced cellular responses yet receptor trafficking induced signaling responses cellular responses receptor trafficking gpcr signaling pharmacological characterization specific receptor signaling compartmentalization initiate signaling xlink "> strong effect spatiotemporal modeling spatial organization spatial localization small fraction refined tool receptors produce methodology offers intracellular compartments including internalization growing number generalizable strategy g protein endosomal sorting endosomal dynamics critical determinants coupled receptors cell surface case study advances understanding <p>Summary of results for the five best models selected based on the AIC criterion. The table below reports the outcomes of the selection procedure for models 3.1, 3.2, 3.3, 3.4 and 3.5, including the answers to 0–0 and the corresponding statistics for each model (negative log-likelihood, AIC, , number of estimated parameters, convergence status), revealing the existence of two distinct model clusters. Convergence was calculated as the number of runs with a negative log-likelihood value below the minimum negative log-likelihood value plus 0.1.</p> 2026-09-29T18:00:32Z Dataset Dataset 10.1371/journal.pcbi.1014790.t001 https://figshare.com/articles/dataset/_p_Summary_of_results_for_the_five_best_models_selected_based_on_the_AIC_criterion_The_table_below_reports_the_outcomes_of_the_selection_procedure_for_models_3_1_3_2_3_3_3_4_and_3_5_including_the_answers_to_0_0_and_the_corresponding_statist/34026726 CC BY 4.0