2026-10-11T20:21:19Z
https://api.figshare.com/v2/oai
oai:figshare.com:article/34026552
2026-09-29T17:32:30Z
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<p>Construction and validation of the <i>S. aureus</i> Δ<i>sph</i> mutant and Δ<i>sph</i>::<i>sph</i> complemented strain. (A) PCR identification of the <i>sph</i> locus and 16S rRNA in WT and Δ<i>sph</i> strains using the indicated primer sets. (B) PCR confirmation of <i>sph</i> in <i>S. aureus</i> WT, Δ<i>sph</i>, and Δ<i>sph</i>::<i>sph</i> strains.</p>
Yunfei Wei (9412265)
Xinyu Zhao (102214)
Ziyi Yin (4117480)
Yanmin Zhang (391964)
Yaxin Zhai (2562517)
Baihe Zhan (25138380)
Yeling Wang (371383)
Jiakang He (16829817)
Jianfeng Wang (232744)
Xuming Deng (158166)
Lei Xu (78676)
Haihua Feng (198813)
Biochemistry
Microbiology
Cell Biology
Genetics
Molecular Biology
Environmental Sciences not elsewhere classified
Immunology
Biological Sciences not elsewhere classified
Science Policy
Infectious Diseases
Virology
mitochondrial contact site
dysregulated inflammatory response
disrupt mammary tissues
potential therapeutic target
key virulence determinant
mastitis remain elusive
dependent ferroptosis contribute
>- induced mastitis
>- induced ferroptosis
sting signaling pathway
mediated mtdna release
cgas ), leading
staphylococcus aureus </
promote gpx4 degradation
aureus </
virulence factors
sting axis
potential role
lysosome pathway
underlying mechanisms
thereby eliciting
sphingomyelin phosphodiesterase
organizing system
micos ).
major pathogen
diverse arsenal
cyclic gmp
core component
amp synthase
>; however
<p>Construction and validation of the <i>S. aureus</i> Δ<i>sph</i> mutant and Δ<i>sph</i>::<i>sph</i> complemented strain. (A) PCR identification of the <i>sph</i> locus and 16S rRNA in WT and Δ<i>sph</i> strains using the indicated primer sets. (B) PCR confirmation of <i>sph</i> in <i>S. aureus</i> WT, Δ<i>sph</i>, and Δ<i>sph</i>::<i>sph</i> strains.</p>
2026-09-29T18:02:15Z
Image
Figure
10.1371/journal.ppat.1014644.s001
https://figshare.com/articles/figure/_p_XXX_p_/34026552
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