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oai:figshare.com:article/34026337 2026-09-29T17:29:58Z category_1 category_4 category_12 category_14 category_15 category_21 category_24 category_45 category_61 category_64 category_132 category_133 portal_5 item_type_6 month_year_09_2026

<p>G proteins show diffusion state-specific differences in mobility.</p> Ondřej Kuchynka (25138312) Andrei Kovalchuk (25138315) Mia Nußbaumer (25138318) Ekaterina Sviridova (25138321) Tomáš Fessl (25138324) Alexey Bondar (665062) Biophysics Biochemistry Cell Biology Molecular Biology Neuroscience Biotechnology Evolutionary Biology Sociology Developmental Biology Cancer Infectious Diseases Plant Biology remain poorly understood physical signals downstream many biophysical aspects key signal transducers findings identify subtype div >< p amplify extracellular chemical g &# 945 specific mobility differences subunits exhibit subtype heterotrimeric g proteins including membrane mobility g proteins membrane mobility g protein plasma membrane xlink "> using single subunit plays signaling dynamics results indicate molecule imaging major role live cells inner leaflet eukaryotic cells different subtypes coupled receptors </ sub <p>A-D) Box plots of median diffusion coefficients of immobile molecules (A) and molecule tracks exhibiting confined (B), free (C), and directed diffusion (D). The boxes indicate the median and the interquartile range. Compact letter display above individual datasets indicates similarity grouping based on statistical analysis (<i>α</i> = 0.05; A: <i>p</i> < 0.0001, <i>H</i> = 36.65, <i>ε</i>^<i>2</i> = 0.29; B: <i>p</i> < 0.0001, <i>H</i> = 46.25, <i>ε</i>^<i>2</i> = 0.41; C: <i>p</i> < 0.0001, <i>H</i> = 54.43, <i>ε</i>^<i>2</i> = 0.49; D: <i>p</i> < 0.0001, <i>H</i> = 23.65, <i>ε</i>^<i>2</i> = 0.20).</p> <p>(PDF)</p> 2026-09-29T17:29:54Z Text Journal contribution 10.1371/journal.pone.0359304.s003 https://figshare.com/articles/journal_contribution/_p_G_proteins_show_diffusion_state-specific_differences_in_mobility_p_/34026337 CC BY 4.0