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oai:figshare.com:article/34026256 2026-09-29T17:29:26Z category_8 category_13 category_14 category_272 category_39 category_46 category_734 category_106 category_122 category_132 category_133 category_134 portal_5 item_type_6 month_year_09_2026

<p>Mutations in the <i>nhre3</i> do not affect the growth and development of <i>Gobiocypris rarus.</i></p> Juhong Xie (25138306) Jiayi Lei (7853165) Qinxue Zhu (25138309) Bin Gui (542725) Yongming Li (584924) Yaping Wang (289641) Rong Huang (298496) Microbiology Genetics Molecular Biology Environmental Sciences not elsewhere classified Ecology Immunology Biological Sciences not elsewhere classified Science Policy Mental Health Infectious Diseases Plant Biology Virology specific ubiquitin ligase significant scientific importance rare minnow (< innate immune regulation immunological arms race grass carp reovirus grass carp (< achieve immune escape gobiocypris rarus </ ctenopharyngodon idella </ virus promotes degradation stimulated gene 15 gchd ), caused >) hemorrhagic diseases viruses exploit ubiquitination host interferon response div >< p ubiquitination plays hemorrhagic disease gene encodes degradation via nhre3 </ gcrv ), viral evasion translational value thereby exerting taken together serious threat random mutagenesis proteasome pathway mechanism unique may represent linked polyubiquitination diverse form central role catalyzing k48 antiviral mechanism ancient origins <p>(A) Comparison of wild-type and mutant <i>Gobiocypris rarus</i> larvae at 4 days post-hatch (dph) showed no significant differences. (B) Comparison of wild-type and mutant <i>Gobiocypris rarus</i> adult fish (approximately 5 months old) showed no significant differences. (C) Comparison of body length between wild-type and mutant <i>Gobiocypris rarus</i> adults (n = 15). No significant difference was observed. (D) Comparison of body weight between wild-type and mutant Gobiocypris rarus adults (n = 15). No significant difference was observed.</p> <p>(DOCX)</p> 2026-09-29T17:29:22Z Text Journal contribution 10.1371/journal.ppat.1014544.s002 https://figshare.com/articles/journal_contribution/_p_Mutations_in_the_i_nhre3_i_do_not_affect_the_growth_and_development_of_i_Gobiocypris_rarus_i_p_/34026256 CC BY 4.0