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oai:figshare.com:article/34025778 2026-09-29T17:25:28Z category_8 category_12 category_15 category_46 category_64 category_122 category_128 category_132 portal_5 item_type_1 month_year_09_2026

<p>Activation of cDCs and pDCs in PBMCs by OLL1073R-1 and OLS3059.</p> Hiroki Kono (2321905) Toshihiro Sashihara (3145098) Microbiology Cell Biology Neuroscience Immunology Cancer Mental Health Hematology Infectious Diseases since several reports play critical roles lactic acid bacteria div >< p inhibiting viral infections viral immune responses plasmacytoid dendritic cells lactobacillus delbrueckii </ streptococcus thermophilus </ conventional dendritic cells ols3059 activate cdcs dendritic cells ols3059 induced anti viral antigens cell responses thermophilus </ l </ bulgaricus </ respiratory symptoms recent studies previous studies interferon production findings indicate components responsible also showed <p>PBMCs are cultured with or without <i>L</i>. <i>bulgaricus</i> OLL1073R-1 or <i>S. thermophilus</i> OLS3059 for 24 h. The expression of CD86, CD40, and HLA-DR in (A) cDCs and (B) pDCs was analyzed by flow cytometry. Representative histograms (black, control; red, OLL1073R-1; blue, OLS3059) and the corresponding geometric mean fluorescent intensity (gMFI) are shown (n = 6). (C) Representative plots of IL-12 expression in cDCs were shown, and the ratio of IL-12 expressing cells in cDCs were analyzed (n = 5). *: <i>p</i> < 0.05, **: <i>p</i> < 0.01, NS: not significant by Dunnett’s test.</p> 2026-09-29T17:25:10Z Image Figure 10.1371/journal.pone.0359545.g001 https://figshare.com/articles/figure/_p_Activation_of_cDCs_and_pDCs_in_PBMCs_by_OLL1073R-1_and_OLS3059_p_/34025778 CC BY 4.0