2026-10-14T05:12:43Z https://api.figshare.com/v2/oai

oai:figshare.com:article/34025574 2026-09-29T17:23:35Z category_4 category_7 category_12 category_14 category_16 category_46 category_61 category_62 category_64 category_132 portal_5 item_type_1 month_year_09_2026

<p>Differential mRNA expression of cytokines in renal tumors and normal tissues from the TCGA-KIRC dataset.</p> Xu Chen (432759) Zhuangyao Liao (10320830) Rochelle Wickramasekara (25138173) Ying Luo (381053) Panning Wang (25138176) Sihao Wang (4577650) Yunru Chen (4351189) Hang Zhou (230977) Shuhong Luo (387711) Shaopeng Qiu (355114) Ruo-Pan Huang (303129) Biochemistry Medicine Cell Biology Molecular Biology Physiology Immunology Developmental Biology Marine Biology Cancer Infectious Diseases using antibody arrays remains poorly defined like receptor pathways invasive biomarker requiring common urological malignancy assessed using gepia analyzed via david tumors versus controls t2 metastatic tumors stage rcc may stage rcc patients urinary erbb3 emerged several cytokines correlated stage tumors rcc patients several cytokine selected cytokines related cytokines urinary erbb3 tumor tissues tumor microenvironment transcriptional expression timer databases survival outcomes stimulating factors serum levels related genes reduced immune poor survival meier plotter inflammatory signals improved outcomes immune infiltration functional enrichment findings suggest elevated pro cytokine signaling cytokine landscape candidate non also reduced 20 sets 174 tumor <p>mRNA expression levels (log2(TPM + 1)) of Angiopoietin-2, IL-2, IL-15, MIG/CXCL9, MIP-1β/CCL4, IGFBP-2, HGF, ErbB3, and Flt-3 Ligand in renal tumors and normal kidney tissues from the TCGA-KIRC dataset. Differential expression analysis was performed using GEPIA with cutoffs of p < 0.05 and |log2FC| > 2.</p> <p>(TIF)</p> 2026-09-29T17:23:34Z Image Figure 10.1371/journal.pone.0358533.s001 https://figshare.com/articles/figure/_p_Differential_mRNA_expression_of_cytokines_in_renal_tumors_and_normal_tissues_from_the_TCGA-KIRC_dataset_p_/34025574 CC BY 4.0