2026-10-07T06:13:29Z https://api.figshare.com/v2/oai

oai:figshare.com:article/34025494 2026-09-29T17:23:02Z category_7 category_12 category_13 category_46 category_734 category_61 category_132 category_135 portal_5 item_type_1 month_year_09_2026

<p>Exploratory endpoint analyses.</p> Qi Cheng (46307) Qunxing Li (6942437) Delu Yin (25138171) Medicine Cell Biology Genetics Immunology Biological Sciences not elsewhere classified Developmental Biology Infectious Diseases Computational Biology traditional diagnostic models reproducible transcriptomic description paired transcriptomic features longitudinal definition criteria evaluate temporal transfer endpoint prediction model directionally concordant longitudinal definitive clinical prediction clinical event prediction adjusted inflammatory burden dynamic immune trajectory transferable across cohorts observed module showed module decreased along external longitudinal cohorts cell atlas suggest impaired inflammatory resolution discovery longitudinal cohort peripheral blood transcriptomes stemi </ p recovery immune axis monocyte state variation baseline module burden failure framework derived stemi immune recovery xlink "> patients one public single associated immune recovery external cohorts impaired resolution discovery cohort blood transcriptomes public peripheral immune recovery xlink "> failure module failure axis module distinguished associated module failure patients sufficient patients state differences exploratory state cell rna cell level cell dataset cell context aware cell failure phenotype <p>Internal classification, GSE59867 heart-failure association, and GSE48060 recurrent-event analyses are presented as exploratory boundary evidence rather than main validation.</p> <p>(TIFF)</p> 2026-09-29T17:22:55Z Image Figure 10.1371/journal.pone.0358983.s006 https://figshare.com/articles/figure/_p_Exploratory_endpoint_analyses_p_/34025494 CC BY 4.0