2026-10-14T22:55:24Z https://api.figshare.com/v2/oai

oai:figshare.com:article/34022855 2026-09-29T10:40:15Z category_37339 category_37354 category_37375 portal_1012 item_type_6 month_year_09_2026

Supplementary Figure 1 from Improving Long-Read Somatic Structural Variant Calling with Pangenome and <i>De Novo</i> Personal Genome Assembly Qian Qin (25136621) Jakob M. Heinz (25136624) Heng Li (9531776) Cancer Molecular and Cellular Biology Methods and Technology Algorithms Computational Methods Software Genome Biology Structural genomics Sequence Analysis <p>Somatic SV calling on matched COLO829 tumor-normal cell lines after downsampling the reads to 50% of the original sequences. A–D. metrics on de novo assembly-based filtering, A. Number of false positive (FP) and true positive (TP) SV calls (C) from PacBio HiFi data at different cutoffs on supporting reads. The solid bars correspond to SV calls still observed in the alignment against the COLO829BL (derived from blood) assembly, while the shaded bars correspond to calls filtered by the assembly. The horizontal line gives the number of ground truth SV calls. B. Number of FP and TP calls (D) from ONT reads.</p> 2026-09-29T00:00:00Z Text Journal contribution 10.1158/2767-9764.34022855 https://figshare.com/articles/journal_contribution/Supplementary_Figure_1_from_Improving_Long-Read_Somatic_Structural_Variant_Calling_with_Pangenome_and_i_De_Novo_i_Personal_Genome_Assembly/34022855 CC BY