2026-10-07T07:09:59Z https://api.figshare.com/v2/oai

oai:figshare.com:article/34020516 2026-09-29T03:16:59Z category_24361 category_24310 item_type_3 month_year_09_2026

Metagenome-assembled genomes of <i>Megasphaera elsdenii</i> from human gut Dina Sabirova (25114149) Microbial genetics Genomics Megasphaera elsdenii metagenome assembled genomes (MAGs) human gut microbiome psoriasis metagenomics <p dir="ltr"><i>Megasphaera elsdenii</i> is a lactate-consuming bacterium found in the rumen and human gut. In this study, we compared 86 <i>M. elsdenii</i> genomes from human feces with animal gut isolates. Phylogenetic analysis revealed a single, genetically homogeneous lineage without host-specific clustering. Human isolates shared most genes and metabolic pathways with swine and cattle isolates. Genome-scale metabolic modeling showed identical carbon and energy requirements, with conserved lactate and acetate utilization across hosts. This dataset contains 11 of these MAGs recovered from human gut metagenomes: 10 from patients with psoriasis and 1 from a healthy control. Raw reads are available in NCBI SRA under BioProjects PRJNA1102742 and PRJNA1061168.</p> 2026-09-29T03:16:59Z Dataset Dataset 10.6084/m9.figshare.34020516.v1 https://figshare.com/articles/dataset/Metagenome-assembled_genomes_of_i_Megasphaera_elsdenii_i_from_human_gut/34020516 CC BY 4.0