2026-10-14T20:47:21Z https://api.figshare.com/v2/oai

oai:figshare.com:article/34018455 2026-09-28T20:48:05Z category_24208 item_type_5 month_year_09_2026

An open source simulation package for coupled biomechanical and biochemical events Norma C. Perez-Rosas (798091) Michael Innerberger (18396100) Ahmed El Hady (7036913) Stephan Preibisch (12975014) Kayvon Pedram (18514047) Bioinformatics and computational biology not elsewhere classified Biomechanics -- Case studies Finite element method Computer programs Biophysical Modeling calcium signal pathways <p dir="ltr">Poster presenting BMBC-Sim (Biomechanics and Biochemistry Simulator), an open-source, Python-based simulation environment for modeling coupled biomechanical and biochemical processes in biological systems. BMBC-Sim enables the definition of complex geometries, material properties, chemical species and their interactions, and the coupling of biochemical and mechanical processes through partial differential equations (PDEs) solved using finite element methods. The poster demonstrates the framework through benchmark problems and applications involving calcium dynamics, complex biological geometries, and concentration-dependent mechanical deformation.</p><p dir="ltr"><br></p><p dir="ltr">Presented at Biology and Engineering of the Cell Surface, HHMI Janelia</p><p dir="ltr">Research Campus, Ashburn, Virginia, USA, October 2025.</p> 2026-09-28T20:48:05Z Image Poster 10.6084/m9.figshare.34018455.v1 https://figshare.com/articles/poster/An_open_source_simulation_package_for_coupled_biomechanical_and_biochemical_events/34018455 CC BY 4.0