2026-10-14T06:01:56Z https://api.figshare.com/v2/oai

oai:figshare.com:article/34018382 2026-09-28T20:01:20Z category_7 category_12 category_15 category_21 category_734 category_61 category_64 category_132 portal_5 item_type_1 month_year_09_2026

<p>The inverted pyramid of care.</p> Laura A. Magee (8788637) Peter von Dadelszen (258508) Kypros H. Nicolaides (10058014) Medicine Cell Biology Neuroscience Biotechnology Biological Sciences not elsewhere classified Developmental Biology Cancer Infectious Diseases provide updated guidance policy forum advocates placenta accreta spectrum advancing gestational age pregnancy complications occur structured risk assessment div >< p inverted &# 8217 improve antenatal care care &# 8217 antenatal care early pregnancy &# 8216 inverted pyramid increased risk building risk xlink "> uteroplacental problems personalised surveillance intrinsic fetal including development enhanced surveillance chromosomal abnormalities become clear artificial intelligence accurate methods accelerating frequency <p>This inverted pyramid of care proposes a focus on the first, rather than the third, trimester of pregnancy. The concept emphasises that many pregnancy complications can be predicted in early pregnancy, by combining maternal history, blood pressure and other biophysical measurements, and biochemical testing. CRM, cardio-renal-metabolic; GDM, gestational diabetes mellitus; LGA, large-for-gestational age; PET, pre-eclampsia; PTB, preterm birth; SGA, small-for-gestational age. * The diagnosis of GDM is usually made at 24–28 weeks’ gestation, by oral glucose tolerance testing.</p> 2026-09-28T20:01:17Z Image Figure 10.1371/journal.pmed.1005255.g001 https://figshare.com/articles/figure/_p_The_inverted_pyramid_of_care_p_/34018382 CC BY 4.0