2026-10-11T14:45:47Z
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2026-09-28T17:58:32Z
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<p>Experimental and best model Relative Position Distributions (RPDs).</p>
Oliver Umney (20106066)
Alistair P. Curd (25132880)
Heather L. Martin (25132883)
Tarek Lewis (25132886)
Anna Ah-San Tang (25132889)
Thembaninkosi Gaule (25132892)
Iain W. Manfield (11978060)
Harikrushnan Balasubramanian (25132895)
Satya Khuon (263722)
Jesse Aaron (197822)
Michelle Peckham (3912823)
Biophysics
Biochemistry
Physical Sciences not elsewhere classified
Cell Biology
Molecular Biology
Physiology
Biotechnology
Immunology
Biological Sciences not elsewhere classified
Developmental Biology
Inorganic Chemistry
Plant Biology
basic repeating unit
div >< p
similar repeating organisation
determine protein organisation
discs </ p
cardiac muscle z
3 key proteins
key role
cardiac signalling
3 </
striated muscle
used perpl
underlying organisation
relative positions
pattern extraction
located within
joined together
fluorescently labelled
discs play
analysis revealed
analyse patterns
3d position
<p>Total model RPD contains terms for the background from randomly distributed localisations, repeated localisation of the same dye molecule and the characteristic distances (d<sub>1</sub>, d<sub>2</sub>, d<sub>3</sub>) between localisations (<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1014309#pcbi.1014309.t002" target="_blank">Tables 2</a>,<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1014309#pcbi.1014309.t003" target="_blank">3</a>, <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1014309#pcbi.1014309.s003" target="_blank">S3</a>-<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1014309#pcbi.1014309.s009" target="_blank">S5</a>). Ratios between modelled distances are shown (e.g., 2d<sub>1</sub>, = 2 x d<sub>1</sub>). 95% confidence intervals shown on total model RPD, only noticeable in A (*).</p>
2026-09-28T18:02:26Z
Image
Figure
10.1371/journal.pcbi.1014309.g002
https://figshare.com/articles/figure/_p_Experimental_and_best_model_Relative_Position_Distributions_RPDs_p_/34017962
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