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<p>Immunogenicity of all <i>P. vivax</i> proteins.</p>
Rosita Asawa (25132843)
Brittany Hazzard (14271698)
Katie Ko (12809883)
Kieran Tebben (14504872)
John Tan (1865173)
Tineke Cantaert (68002)
Andrea Berry (6244949)
Niraj Tolia (25132846)
Jean Popovici (423629)
David Serre (2815)
Physical Sciences not elsewhere classified
Medicine
Microbiology
Biotechnology
Immunology
Biological Sciences not elsewhere classified
Hematology
Infectious Diseases
select vaccine candidates
host immune system
entire protein sequences
develop new tools
density peptide array
analyses also revealed
5 billion people
analyzed antibody responses
many uncharacterized proteins
plasmodium vivax </
clinical vivax malaria
plasmodium </
vivax </
clinical importance
antibody response
wide perspective
wide characterization
unique pattern
symptomatic individuals
stage infections
several nucleoporins
naïve individuals
malaria community
infection worldwide
important resource
erythrocyte invasion
data provide
better detecting
asymptomatic individuals
antigens using
<p>The table indicates, for each protein-coding gene, the number of patients with antibody binding in our analyses (out of ten). Proteins recognized in seven or more patients were deemed immunogenic and are indicated in bold. The table also includes, for comparison, the results from Chuquiyauri et al., Am. J. Trop. Med. Hyg. (2015) and Longley et al., PLoS Negl. Trop. Dis. (2017) (NA: not tested, Yes: immunogenic, No: not immunogenic), as well as the orthologs in other <i>Plasmodium</i> species.</p> <p>(TIF)</p>
2026-09-28T17:53:52Z
Image
Figure
10.1371/journal.ppat.1014621.s016
https://figshare.com/articles/figure/_p_Immunogenicity_of_all_i_P_vivax_i_proteins_p_/34017742
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