2026-10-10T03:25:50Z
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2026-09-28T17:53:07Z
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<p>Association between the average level of mRNA expression of a gene in blood stage parasites and protein antigenicity.</p>
Rosita Asawa (25132843)
Brittany Hazzard (14271698)
Katie Ko (12809883)
Kieran Tebben (14504872)
John Tan (1865173)
Tineke Cantaert (68002)
Andrea Berry (6244949)
Niraj Tolia (25132846)
Jean Popovici (423629)
David Serre (2815)
Physical Sciences not elsewhere classified
Medicine
Microbiology
Biotechnology
Immunology
Biological Sciences not elsewhere classified
Hematology
Infectious Diseases
select vaccine candidates
host immune system
entire protein sequences
develop new tools
density peptide array
analyses also revealed
5 billion people
analyzed antibody responses
many uncharacterized proteins
plasmodium vivax </
clinical vivax malaria
plasmodium </
vivax </
clinical importance
antibody response
wide perspective
wide characterization
unique pattern
symptomatic individuals
stage infections
several nucleoporins
naïve individuals
malaria community
infection worldwide
important resource
erythrocyte invasion
data provide
better detecting
asymptomatic individuals
antigens using
<p>The x-axis shows 100 bins of 66 <i>P. vivax</i> genes grouped according to their average mRNA expression in blood stage parasites (black line, right y-axis) and ranked from left (most expressed genes) to right (least expressed genes). The vertical bars indicate the number of antigenic proteins in each bin (left y-axis).</p> <p>(TIF)</p>
2026-09-28T17:53:52Z
Image
Figure
10.1371/journal.ppat.1014621.s007
https://figshare.com/articles/figure/_p_Association_between_the_average_level_of_mRNA_expression_of_a_gene_in_blood_stage_parasites_and_protein_antigenicity_p_/34017715
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