2026-10-12T12:06:04Z https://api.figshare.com/v2/oai

oai:figshare.com:article/34017694 2026-09-28T17:52:56Z category_12 category_13 category_15 category_272 category_734 category_61 category_64 category_128 category_133 portal_5 item_type_1 month_year_09_2026

<p>Annotation of optic lobe glia in the larval and adult single-cell datasets.</p> Amanda A. G. Ferreira (25132828) Sergio Córdoba (645937) Raghuvanshi Rajesh (25132831) Ben Jiwon Choi (25132834) Claude Desplan (45436) Cell Biology Genetics Neuroscience Environmental Sciences not elsewhere classified Biological Sciences not elsewhere classified Developmental Biology Cancer Hematology Plant Biology innovative computational approach genetic markers expressed div >< p subcellular mrna compartmentalization optic lobe glia two large single detailed transcriptomic analysis identify mrna species glial diversity observed adult visual system glial cell bodies glial cell types understand glial development visual system cell mrna cell bodies glial types glial cells glia types adult stages cell class cell atlas neuropil glia chiasm glia work provides transcriptionally appear pupal stages helps explain gradually change drosophila </ distinct mrnas differentially localized developmental trajectories developmental single comprehensively annotated also present allowed us <p><b>(A)</b> A cross-section schematic representation of the larva (L3) optic lobe with the glial cell types depicted. <b>(B)</b> UMAP visualization of the final larval glial cells annotations after removal of cellular processes in the dataset (<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3004015#pbio.3004015.s009" target="_blank">S1 Table</a>). Colors of the clusters match the colors in the drawing in (A). <b>(C)</b> A cross-section schematic representation of the adult stage optic lobe with the glial cell types depicted. <b>(D)</b> TSNE visualization of the final adult stage glial cells annotations after removal of cellular processes in the dataset (<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3004015#pbio.3004015.s010" target="_blank">S2 Table</a>). The colors of the clusters match the colors in the drawing in (C).</p> 2026-09-28T17:57:37Z Image Figure 10.1371/journal.pbio.3004015.g007 https://figshare.com/articles/figure/_p_Annotation_of_optic_lobe_glia_in_the_larval_and_adult_single-cell_datasets_p_/34017694 CC BY 4.0